Results 51 to 60 of about 2,996,306 (294)

Early – versus late-onset preeclampsia: differences in risk factors and birth outcomes

, 2017
Introduction. Preeclampsia (PE) continues to be a leading cause of maternal and fetal morbidity and mortality worldwide with an incidence of 3–5 %. Recently evidence suggests that PE can be subdivided into early-onset PE (EOP), requiring delivery before ...
Medvyedyeva O., Markin L.
core   +1 more source

Serum levels of GDF15 are reduced in preeclampsia and the reduction is more profound in late-onset than early-onset cases [PDF]

, 2016
Background: Preeclampsia is a pregnancy specific disorder affecting 3-5% of pregnancies worldwide. It is clinically divided into early-onset and late-onset subtypes. Placental factors are involved in the pathogenesis of preeclampsia.
Fabricio da Silva Costa, Min Zhao, da Silva Costa, Fabricio, Yao Wang, Chen, Qi, Zhao, Min, Jonathan Hyett, Wang, Yao, Guiying Nie, Hyett, Jon A. (R20572), Hyett, Jonathan, Nie, Guiying, Costa, Fabricio da Silva, Qi Chen   +13 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Epidemiology of Late-onset Schizophrenia [PDF]

Schizophrenia Bulletin, 1993
We report an analysis of a large catchment area sample of patients with nonaffective functional psychoses presenting across all ages at onset. The male:female ratio was 1.56:1 in the 16-25-year age group; it reached unity around 30 years of age and declined to 0.38:1 in the 66-75-year group. Contrary to expectation, a higher proportion of patients with
D J, Castle, R M, Murray
openaire   +2 more sources

Applying machine learning techniques to the identification of late-onset hypogonadism in elderly men

, 2017
In the diagnosis of late-onset hypogonadism (LOH), the Androgen Deficiency in the Aging Male (ADAM) questionnaire or Aging Males' Symptoms (AMS) scale can be used to assess related symptoms.
Lu, Ti;Hu, Ya-Han;Tsai, Chih-Fong;Liu, Shih-Ping;Chen, Pei-Ling, 劉詩彬   +1 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Survival of Hepatocellular Carcinoma: A Comprehensive Study on the Impact of Early versus Late Onset and Its Determinants

Jurnal Penyakit Dalam Indonesia
Introduction. The prognosis for patients with Hepatocellular Carcinoma (HCC) is generally poor because most cases are diagnosed at an advanced stage. Several studies indicate that HCC is more prevalent and has a worse prognosis among younger individuals.
Ibrahim Achmad, Chyntia Olivia Maurine Jasirwan, Wulyo Rajabto, Murdani Abdullah, Saut Horas H. Nababan, Sally Aman Nasution, Sukamto Koesnoe, Nina Kemala Sari   +7 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Late onset clozapine induced agranulocytosis

Indian Journal of Psychological Medicine, 2014
Agranulocytosis is defined as an absolute neutrophil count less than 100/mm 3 in association with infectious disease. The risk of agranulocytosis is 0.38% of all clozapine treated cases and there is a relatively lesser incidence in Indian population. The
Rajmohan Velayudhan, Sushil Kakkan
doaj   +1 more source