Multimorbidity patterns and their associations with patient-perceived treatment burden: A latent class analysis of 14,344 Danish adults. [PDF]
Pedersen MH +6 more
europepmc +1 more source
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
Trajectories of Childhood Housing Insecurity and Links to Emerging Adulthood Depression: A Repeated Measures Latent Class Approach. [PDF]
Marçal K.
europepmc +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
The Association Between Lifestyle Patterns and Depression in United States Emerging Adults: A Latent Class Analysis. [PDF]
Armstrong N +5 more
europepmc +1 more source
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Attitudinal Profiles Toward Medical Mediation Among Healthcare Professionals: Evidence from a Scenario-Based Survey and Latent Class Analysis. [PDF]
Lioupi O +4 more
europepmc +1 more source
The device exhibits excellent ferroelectric performance and significant photoelectric response. It can adapt to light stimuli of varying power and wavelengths while achieving a stable and tunable photovoltaic response state. Moreover, the device can utilize photoconductive states of different directions and magnitudes to achieve pattern classification ...
Zhen Zhao +21 more
wiley +1 more source
Self-stigma profiles in schizophrenia: a Latent Class Analysis approach. [PDF]
Caqueo-Urízar A +4 more
europepmc +1 more source
Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio +3 more
wiley +1 more source

