Results 301 to 310 of about 1,520,947 (358)

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Latent Class Analysis to Identify Novel Phenotypes in Exacerbations of COPD: A Retrospective, Multicenter Cohort Study. [PDF]

MedComm (2020)
Hou X, Deng Z, Zhou Y, Hong J, Wu F, Li Y, Huang J, Dai C, Lu L, Tang G, Wan Q, Zhou K, Wu X, Peng J, Zhu L, Chen X, Ran P.   +16 more
europepmc   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

Advanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang, Zhishen Cai, Xingfeng Mao, Yixuan Zhang, Yunlong Pan, Jiawen Cheng, Xuechun Wang, Hengyi Song, Sasaki Takuya, Ming Lu, Gang Hu, Xiuxiu Liu, Yingmei Lu, Feng Han   +13 more
wiley   +1 more source

Social wellbeing, loneliness, and symptom burden in head and neck cancer survivors: a latent class analysis. [PDF]

J Psychosoc Oncol
Brauer ER, Choi KR, Petersen L, Ganz PA, St John MA, Wong DJ, Martin EJ.   +6 more
europepmc   +1 more source

Early childhood risk and protective factors and their association with adolescent sexual behaviors: A Latent Class Analysis. [PDF]

PLoS One
Liu Q, Vasilenko SA, Wang X, Razza RA.
europepmc   +1 more source

Risk-taking behaviors in relation to religiosity and familial support among university students: a latent class analysis. [PDF]

BMC Public Health
Tebyanian M, Ataee S, Abbasi-Ghahramanloo A, Afrashteh S, Sabaghan M, Imani M, Alizadeh-Barzian K, Movahednia Z, Daneshi N.   +8 more
europepmc   +1 more source

Investigating multimorbidity patterns and associated risk factors in the fasa adults cohort study (FACS): A latent class analysis. [PDF]

PLoS One
Sharafi M, Baeradeh N, Mohsenpour MA, Afrashteh S, Bagheri P, Keshavarzian O, Annabi MA, Nekouei F, Farjam M.   +8 more
europepmc   +1 more source