Rethinking genomic selection under environmental uncertainty: toward learnable and dynamic environmental representations. [PDF]
Yan J, Wang X.
europepmc +1 more source
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu +6 more
wiley +1 more source
Latent classification of time-dependent transition rates in longitudinal binary outcome data. [PDF]
Chang J, Chan W.
europepmc +1 more source
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li +12 more
wiley +1 more source
Psychopathological Risk During Adolescent Study-Abroad: A Larger-Cohort Update of a Previous Longitudinal Study. [PDF]
Cimino S, Cerniglia L.
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Trajectories of Nonrestorative Sleep in First-year College Students: The Roles of Childhood Emotional Abuse and Resilience. [PDF]
Liao W, Luo X, Sun Y, Kong F, Ye Z.
europepmc +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
A national growth mixture modeling analysis of county-level COVID-19 incidence rate trajectories and health inequities during three successive pandemic waves in 2020. [PDF]
Dukes K +15 more
europepmc +1 more source

