Results 91 to 100 of about 17,167,783 (309)

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

Impact of "Seguro Popular" on Prenatal Visits in Mexico, 2002-2005: Latent Class Model of Count Data with a Discrete Endogenous Variable [PDF]

open access: yes
We employ a latent class model to assess the impact of Mexico's Seguro Popular ("SP") program on the number of prenatal visits in a cross-sectional sample of 4,381 women who gave birth during 2002-2005.
Jeffrey E. Harris, Sandra G. Sosa-Rubi
core  

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter   +5 more
wiley   +1 more source

Reassessing the Link between Voter Heterogeneity and Political Accountability: A Latent Class Regression Model of Economic Voting [PDF]

open access: yes, 2009
While recent research has underscored the conditioning effect of individual characteristics on economic voting behavior, most empirical studies have failed to explicitly incorporate observed heterogeneity into statistical analyses linking citizens ...
Katz, Gabriel, Katz, Jonathan N.
core  

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo   +11 more
wiley   +1 more source

Parkinson Disease Subtype Stability and Eventual Convergence

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok   +10 more
wiley   +1 more source

Assessment of the general public's knowledge about rheumatic diseases: evidence from a Portuguese population-based survey

open access: yesBMC Musculoskeletal Disorders, 2010
Background To identify incorrect beliefs and common knowledge about rheumatic diseases in the general population. Methods Participants were selected during the follow-up of a representative cohort of adult population of Porto, Portugal; 1626 participants
Severo Milton   +3 more
doaj   +1 more source

A latent class model for competing risks.

open access: yesStatistics in medicine, 2017
Survival data analysis becomes complex when the proportional hazards assumption is violated at population level or when crude hazard rates are no longer estimators of marginal ones. We develop a Bayesian survival analysis method to deal with these situations, on the basis of assuming that the complexities are induced by latent cohort or disease ...
Rowley, M.   +10 more
openaire   +4 more sources

Extending dynamic segmentation with lead generation: A latent class Markov analysis of financial product portfolios [PDF]

open access: yes
A recent development in marketing research concerns the incorporation of dynamics in consumer segmentation.This paper extends the latent class Markov model, a suitable technique for conducting dynamic segmentation, in order to facilitate lead generation ...
Vermunt, J.K.   +2 more
core  

Characterizing longitudinal patterns of physical activity in mid-adulthood using latent class analysis: results from a prospective cohort study. [PDF]

open access: yes, 2011
The authors aimed to describe how longitudinal patterns of physical activity during mid-adulthood (ages 31-53 years) can be characterized using latent class analysis in a population-based birth cohort study, the Medical Research Council's 1946 National ...
G. D. Mishra   +11 more
core   +1 more source

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