From Agreement to Epistemic Alignment: A Signal Detection-Theoretic Model of Inter-Rater Reliability. [PDF]
Gianeselli I.
europepmc +1 more source
Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source
Quantum-enhanced multimodal prognostic transformer for skin disease progression prediction and visualization. [PDF]
Aravinda CV, Raja JE, Alasmari S.
europepmc +1 more source
Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu +15 more
wiley +1 more source
An unfavorable biologic profile associated with decreased overall survival and cancer-specific survival in non-metastatic breast cancer: A latent class analysis. [PDF]
Falandry C +9 more
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Psychological and lifestyle correlates of eating behavior and adiposity: Structural and latent profile modeling. [PDF]
Obara-Gołębiowska M.
europepmc +1 more source
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
The latent structure of ICD-11 Prolonged Grief: Replicated factor mixture models in two national cohorts. [PDF]
Cunningham J, Shevlin M, McElroy E.
europepmc +1 more source

