Results 271 to 280 of about 1,514,883 (344)

Assessing diagnostic accuracy of Ov16 rapid diagnostic tests for onchocerciasis using Bayesian latent class models

Jayla Norman, N'Deye-Marie Bassabi-Alladjie, Pélagie Boko-Collins, Dziedzom K. de Souza, Katie Gass, Louise Hamill, Jerónimo S. Langa, Carson Paige Moore, Rassul Nalá, Sarah Mary Sullivan, Emanuele Giorgi   +10 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Trajectories of cigarette smoking and exposure to welding fumes and their impact on lung cancer risks: a latent class modelling approach. [PDF]

BMJ Open
Kendzia B, Taeger D, Pohabeln H, Ahrens W, Wichmann HE, Jöckel KH, Brüning T, Behrens T.   +7 more
europepmc   +1 more source

Latent Class Models in the Assessment of Education: The Case of Students’ Academic Attainment in Elementary Education in Zacatecas Modelos de Clase Latente en la Evaluación de la Educación. El Caso del Aprovechamiento Escolar en la Educación Primaria de Zacatecas.

, 2008
Francisco Muro González
openalex   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Cognitive and Mental Health Differences Across Latent Profiles of Religiosity and Spirituality in Korean Older Adults With Mild Cognitive Impairment or Alzheimer's Disease. [PDF]

Am J Alzheimers Dis Other Demen
Hur M, Kim M, Min S, Lee CH, Kim DH.
europepmc   +1 more source

Trajectories of Depressive Symptoms among Multicultural Middle and High School Adolescents: A Longitudinal Study Using Latent Class Growth Model

Sujin Lee, Soo Jin Lee, Hwa-Sun Kim
openalex   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

Advanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger, Paolo Cardone, Charlotte Martial, Yonatan Sanz Perl, Iván Mindlin, Jacobo D Sitt, Leor Roseman, Robin Carhart‐Harris, David Nutt, Pablo Mallaroni, Natasha Mason, Johannes G Ramaekers, Vincent Bonhomme, Steven Laureys, Gustavo Deco, Olivia Gosseries, Pablo Núñez, Jitka Annen   +17 more
wiley   +1 more source

Smoking reduction trajectories and their association with smoking cessation: a secondary analysis of longitudinal clinical trial data. [PDF]

BMJ Public Health
Barrows A, Klemperer E, Garavan H, Allgaier N, Lindson N, Taylor G.   +5 more
europepmc   +1 more source