Results 281 to 290 of about 1,514,883 (344)

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

Patterns of alcohol use and response to digital brief interventions in college students: a secondary analysis of a cluster randomized trial. [PDF]

open access: yesFront Psychiatry
Ghosh A   +8 more
europepmc   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

open access: yesAdvanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang   +13 more
wiley   +1 more source

A Combinatorial Approach to Synthetic Data Generation for Machine Learning. [PDF]

open access: yesSN Comput Sci
Khadka K   +4 more
europepmc   +1 more source

Epigenetic aging and lifespan reflect reproductive history in the Finnish Twin Cohort. [PDF]

open access: yesNat Commun
Hukkanen M   +5 more
europepmc   +1 more source

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