Results 51 to 60 of about 79,128 (266)

Progression of erectile function in men with chronic obstructive pulmonary disease: a cohort study

BMC Pulmonary Medicine, 2019
Background Although sexual function is a quality of life aspect that is markedly affected in males with chronic obstructive pulmonary disease (COPD), this topic has not attracted much attention and research on this matter is lacking.
Eui Geum Oh, Jae Yong Yoo
doaj   +1 more source

Maternal vitamin D status in relation to infant BMI growth trajectories up to 2 years of age in two prospective pregnancy cohorts

Obesity Science & Practice, 2022
Background Early childhood growth can affect the child's health status later in life. Maternal vitamin D status has been suggested to affect early childhood growth.
Anna Amberntsson, Linnea Bärebring, Anna Winkvist, Lauren Lissner, Helle Margrete Meltzer, Anne Lise Brantsæter, Eleni Papadopoulou, Hanna Augustin   +7 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Childhood adiposity trajectories are associated with late adolescent blood pressure: birth to twenty cohort

BMC Public Health, 2016
Background Elevated blood pressure in childhood is a risk factor for adult hypertension which is a global health problem. Excess adiposity in childhood creates a predisposition to develop adult hypertension.
Richard J. Munthali, Juliana Kagura, Zané Lombard, Shane A. Norris   +3 more
doaj   +1 more source

Latent Class Trajectory and Growth Mixture Models in the Study of Physical Resilience [PDF]

Innovation in Aging, 2020
Abstract After a stressor, individuals may experience different trajectories of function and recovery. One potential explanation for this variation is differing trajectories may be indicators of differing classes or levels of resilience to the stressor.
Pieper, Carl, Pendergast, Jane, Neely, Megan   +2 more
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Trajectories of Postpartum Depression in Italian First-Time Fathers

American Journal of Men's Health, 2017
Paternal postpartum depression (PPD) has received little attention compared with maternal prenatal and postpartum depression, despite research reporting that paternal PPD concerns a substantial number of fathers.
Sara Molgora PhD, Valentina Fenaroli PhD, Matteo Malgaroli MS MPhil, Emanuela Saita PhD   +3 more
doaj   +1 more source

Bayesian modeling of networks in complex business intelligence problems

, 2016
Complex network data problems are increasingly common in many fields of application. Our motivation is drawn from strategic marketing studies monitoring customer choices of specific products, along with co-subscription networks encoding multiple ...
Airoldi, Aldous, Azzalini, Banerjee, Bhattacharya, Bigelow, Dunson, Escobar, Fruchterman, Gershman, Griffiths, Hjort, Hoff, Hoff, Kaishev, Kamakura, Kamakura, Lau, Matiş, Medvedovic, Neal, Nowicki, Polson, Rousseau, Stephens, Thuring, Thuring, Verhoef   +27 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source