Results 61 to 70 of about 79,128 (266)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Exploring the Patterns of Skill Development by Mixture Growth Modeling: Using the Batting Average Data on Professional Baseball Players [PDF]

, 2008
　Reviewing latent growth modeling for longitudinal data and some results using this methodology on career development, mixture modeling methodologies were introduced for identifying clusters of individuals following similar developmental trajectories ...
Shimizu Kazuaki, 清水 和秋
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

How do teacher support trajectories influence primary and lower-secondary school students’ study well-being

Frontiers in Psychology, 2023
Effective long term teacher support is key to promoting and sustaining students’ study well-being at school. However, little is known about individual variations in the development of perceived teacher support and how such variations are associated with ...
Sanna Ulmanen, Sanna Ulmanen, Pihla Rautanen, Tiina Soini, Janne Pietarinen, Kirsi Pyhältö, Kirsi Pyhältö   +6 more
doaj   +1 more source

Formal and Informal Model Selection with Incomplete Data

, 2008
Model selection and assessment with incomplete data pose challenges in addition to the ones encountered with complete data. There are two main reasons for this.
Beunckens, Caroline, Molenberghs, Geert, Verbeke, Geert   +2 more
core   +1 more source

Hippocampal subfields and limbic white matter jointly predict learning rate in older adults

, 2020
First published online: 04 December 2019Age-related memory impairments have been linked to differences in structural brain parameters, including cerebral white matter (WM) microstructure and hippocampal (HC) volume, but their combined influences are ...
Bender, A., Brandmaier, A., Düzel, S., Keresztes, A., Kühn, S., Lindenberger, U., Pasternak, O.   +6 more
core   +1 more source

Latent Markov and growth mixture models for ordinal individual responses with covariates: A comparison [PDF]

Statistical Analysis and Data Mining: The ASA Data Science Journal, 2017
AbstractObjectiveWe review two alternative ways of modeling stability and change of longitudinal data by using time‐fixed and time‐varying covariates for the observed individuals. Both the methods build on the foundation of finite mixture models, and are commonly applied in many fields but they look at the data from different perspectives.
PENNONI, FULVIA, Romeo, I.
openaire   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Posterior Contraction Rates of the Phylogenetic Indian Buffet Processes [PDF]

, 2015
By expressing prior distributions as general stochastic processes, nonparametric Bayesian methods provide a flexible way to incorporate prior knowledge and constrain the latent structure in statistical inference.
Chen, Mengjie, Gao, Chao, Zhao, Hongyu
core   +3 more sources

Phase Field Failure Modeling: Brittle‐Ductile Dual‐Phase Microstructures under Compressive Loading

Advanced Engineering Materials, EarlyView.
The approach by Amor and the approach by Miehe and Zhang for asymmetric damage behavior in the phase field method for fracture are compared regarding their fitness for microcrack‐based failure modeling. The comparison is performed for the case of a dual‐phase microstructure with a brittle and a ductile constituent.
Jakob Huber, Jan Torgersen, Ewald Werner
wiley   +1 more source