Results 71 to 80 of about 6,143,323 (339)

Discussion: Latent variable graphical model selection via convex optimization

open access: yes, 2012
Discussion of "Latent variable graphical model selection via convex optimization" by Venkat Chandrasekaran, Pablo A. Parrilo and Alan S. Willsky [arXiv:1008.1290].Comment: Published in at http://dx.doi.org/10.1214/12-AOS984 the Annals of Statistics ...
Giraud, Christophe, Tsybakov, Alexandre
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

A Latent Factor Analysis of Working Memory Measures Using Large-Scale Data

open access: yesFrontiers in Psychology, 2017
Working memory (WM) is a key cognitive system that is strongly related to other cognitive domains and relevant for everyday life. However, the structure of WM is yet to be determined.
Otto Waris   +9 more
doaj   +1 more source

Multilevel (ML-ICLV) & Single Level Integrated Discrete Choice and Latent Variable (ICLV) Models Using Alternative Latent Structures' Conceptualizations [PDF]

open access: yes, 2013
The aim of the present endeavor is to experiment on integrating discrete choice with latent variable (ICVL) models using alternative factorial structures’ conceptualizations and do so at both Single Level (Level 0) and Multilevel (ML-ICVL).
Chrysochoidis, Georgios, Wilson, Charlie
core  

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow   +4 more
wiley   +1 more source

Application of a joint multivariate probit model for mixed outcomes of CD4 cell count and tuberculosis using a Bayesian latent variable approach in KwaZulu-Natal

open access: yesFrontiers in Applied Mathematics and Statistics
HIV and tuberculosis (TB) remain closely linked public health threats in sub-Saharan Africa, with South Africa bearing the highest burden of both diseases.
Exaverio Chireshe   +5 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Modular Jump Gaussian Processes

open access: yesData Science in Science
Gaussian processes (GPs) furnish accurate nonlinear predictions with well-calibrated uncertainty. However, the typical GP setup has a built-in stationarity assumption, making it ill-suited for modeling data from processes with sudden changes, or “jumps ...
Anna R. Flowers   +4 more
doaj   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

open access: yesArthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim   +18 more
wiley   +1 more source

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