Results 81 to 90 of about 679,297 (329)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Tensors and Latent Variable Models [PDF]

open access: yes, 2015
In this paper we discuss existing and new connections between latent variable models from machine learning and tensors multi-way arrays from multilinear algebra. A few ideas have been developed independently in the two communities. However, there are still many useful but unexplored links and ideas that could be borrowed from one of the communities and
openaire   +2 more sources

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Non-Markovian regime switching with endogenous states and time-varying state strengths [PDF]

open access: yes
This article presents a non-Markovian regime switching model in which the regime states depend on the sign of an autoregressive latent variable. The magnitude of the latent variable indexes the 'strength' of the state or how deeply the system is embedded
Michael J. Dueker, Siddhartha Chib
core  

A Zero-Inflated Box-Cox Normal Unipolar Item Response Model for Measuring Constructs of Psychopathology [PDF]

open access: yes, 2018
This research introduces a latent class item response theory (IRT) approach for modeling item response data from zero-inflated, positively skewed, and arguably unipolar constructs of psychopathology. As motivating data, the authors use 4,925 responses to
Liu, Yang, Magnus, Brooke E.
core   +1 more source

Preferences for Posttraumatic Osteoarthritis Prevention Strategies in Individuals With Anterior Cruciate Ligament Injury

open access: yesArthritis Care &Research, EarlyView.
Objective There is growing interest in evaluating new strategies to delay or prevent posttraumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury. Methods Participants with a history of
Kevin Kennedy   +9 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

VARIABEL LATEN SEBAGAI MODERATOR DAN MEDIATOR DALAM HUBUNGAN KAUSAL

open access: yesE-Jurnal Matematika, 2013
Latent variables are variables that can not be measured directly. In analysis of causal relationship involving three latent variables, one latent variable can be a moderator or mediator variables. Goodness of Fit moderation and mediation model of latent
I KOMANG GEDE ANTARA   +2 more
doaj   +1 more source

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