Results 31 to 40 of about 186,339 (256)

Statistical Modeling of Phenotypic Plasticity under Abiotic Stress in Triticum durum L. and Triticum aestivum L. Genotypes

open access: yesAgronomy, 2018
Future challenges to the role of durum and bread wheat in global food security will be shaped by their potential to produce larger yields and better nutritional quality, while increasingly adapting to multiple biotic and abiotic stresses in the view of ...
Abdullah A. Jaradat
doaj   +1 more source

Latent class instrumental variables and the monotonicity assumption

open access: yesEmerging Themes in Epidemiology, 2020
A key aspect of the article by Lousdal on instrumental variables was a discussion of the monotonicity assumption. However, there was no mention of the history of the development of this assumption.
Stuart G. Baker
doaj   +1 more source

Low-Dimensional Dynamics of Brain Activity Associated with Manual Acupuncture in Healthy Subjects

open access: yesSensors, 2021
Acupuncture is one of the oldest traditional medical treatments in Asian countries. However, the scientific explanation regarding the therapeutic effect of acupuncture is still unknown.
Xinmeng Guo, Jiang Wang
doaj   +1 more source

Tutorial on the Use of the regsem Package in R

open access: yesPsych, 2021
Sparse estimation through regularization is gaining popularity in psychological research. Such techniques penalize the complexity of the model and could perform variable/path selection in an automatic way, and thus are particularly useful in models that ...
Xiaobei Li   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Tensors and Latent Variable Models [PDF]

open access: yes, 2015
In this paper we discuss existing and new connections between latent variable models from machine learning and tensors multi-way arrays from multilinear algebra. A few ideas have been developed independently in the two communities. However, there are still many useful but unexplored links and ideas that could be borrowed from one of the communities and
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Relationship of Causal Factors in the Economic, Social, and Environmental Aspects Affecting the Implementation of Sustainability Policy in Thailand: Enriching the Path Analysis Based on a GMM Model

open access: yesResources, 2018
This research aimed to analyze the influence of the direct and indirect relationships of economic, social, and environmental factors as well as predict their future effects by applying a path analysis of a generalized method of moments model (path ...
Pruethsan Sutthichaimethee   +1 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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