Results 41 to 50 of about 1,039,444 (298)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Observing mesoscale eddy effects on mode-water subduction and transport in the North Pacific

open access: yesNature Communications, 2016
Physical processes by which mesoscale eddies affect subduction remain unclear. Here, through a specially designed eddy-resolving field experiment, the authors capture the eddy enhancement of mode water subduction and transport, and confirm the dominance ...
Lixiao Xu   +5 more
doaj   +1 more source

Quantitative Analysis of Blood Flow in Cerebral Venous Sinus With Stenosis by Patient-Specific CFD Modeling

open access: yesIEEE Access, 2019
Hemodynamics analysis of the cerebral venous sinus (CVS) is important to the etiologies of idiopathic intracranial hypertension (IIH) and pulsatile tinnitus (PT).
Xin Liu   +8 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Relationship between the geometry patterns of vertebrobasilar artery and atherosclerosis

open access: yesBMC Neurology, 2018
Background The plaques at the dorsal or lateral wall of basilar artery (BA) are associated with pontine infarcts. We sought to explore the correlations between vertebrobasilar artery geometry and BA plaque locations.
Jin Yu   +9 more
doaj   +1 more source

Dominance solvability of dynamic bargaining games [PDF]

open access: yes, 2009
Backward induction, Coalition, Core, Weak dominance, C78, D71, D74,
Christopher Tyson   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Anatomical variations of dominant anastomotic veins in the superficial cortical venous system

open access: yesTranslational Research in Anatomy, 2022
Background: Understanding the anatomy of the anastomotic veins (AV) of the superficial cortical venous system (SCVS), viz. Superficial Sylvian vein (SSV) - also known as the superficial middle cerebral vein; vein of Labbe (VL) and vein of Trolard (VT ...
Joastin Naidoo   +2 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

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