Results 121 to 130 of about 5,621,877 (267)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

The Mitogenome of Sedum plumbizincicola (Crassulaceae): Insights into RNA Editing, Lateral Gene Transfer, and Phylogenetic Implications. [PDF]

Biology (Basel), 2022
Ding H, Bi, Zhang S, Han S, Ye Y, Yi R, Yang J, Liu B, Wu L, Zhuo R, Kan X.   +10 more
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Comparative genomic study of the Penicillium genus elucidates a diverse pangenome and 15 lateral gene transfer events. [PDF]

IMA Fungus, 2023
Petersen C, Sørensen T, Nielsen MR, Sondergaard TE, Sørensen JL, Fitzpatrick DA, Frisvad JC, Nielsen KL.   +7 more
europepmc   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

High Frequency of Horizontal Gene Transfer in the Oceans

, 2010
Viruslike particles enable lateral gene transfer among marine microorganisms.
Lauren D. McDaniel, John H. Paul, Kim B. Ritchie, Jennifer Delaney, Fabian Ruhnau, Elizabeth Young   +5 more
core   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

Could Horizontal Gene Transfer Explain 5S rDNA Similarities Between Frogs and Worm Parasites?

Biomolecules
Horizontal gene transfer (HGT), the non-Mendelian transfer of genetic material between organisms, is relatively frequent in prokaryotes, whereas its extent among eukaryotes remains unclear.
Kaleb Pretto Gatto, Cintia Pelegrineti Targueta, Stenio Eder Vittorazzi, Luciana Bolsoni Lourenço   +3 more
doaj   +1 more source

<i>Orientia tsutsugamushi:</i> comprehensive analysis of the mobilome of a highly fragmented and repetitive genome reveals the capacity for ongoing lateral gene transfer in an obligate intracellular bacterium. [PDF]

mSphere, 2023
Giengkam S, Kullapanich C, Wongsantichon J, Adcox HE, Gillespie JJ, Salje J.   +5 more
europepmc   +1 more source

Liquid Metal Resistive Sensing Architectures for Measuring Diaphragm Strain Responses on Obstructed Surfaces

Advanced Materials Technologies, EarlyView.
A liquid metal‐based strain‐sensing architecture to measure the deformation of a circular diaphragm against obstructed surfaces is formulated using finite element modeling and confocal imaging to establish the mechanical framework and is utilized to control diaphragm‐induced confinement on a bead array, as validated by biomolecular loading level ...
Abdullah‐Bin Siddique, Jui‐Hong Weng, Deng‐Kai Yang, Chia‐Fu Chou, Nathan S. Swami   +4 more
wiley   +1 more source