Results 71 to 80 of about 5,304,033 (262)

Uncovering rate variation of lateral gene transfer during bacterial genome evolution

BMC Genomics, 2008
Background Large scale genome arrangement, such as whole gene insertion/deletion, plays an important role in bacterial genome evolution. Various methods have been employed to study the dynamic process of gene insertions and deletions, such as parsimony ...
Golding G Brian, Hao Weilong
doaj   +3 more sources

A Bayesian Method for Analyzing Lateral Gene Transfer [PDF]

Systematic Biology, 2014
Lateral gene transfer (LGT)--which transfers DNA between two non-vertically related individuals belonging to the same or different species--is recognized as a major force in prokaryotic evolution, and evidence of its impact on eukaryotic evolution is ever increasing.
Sjöstrand, Joel, Tofigh, Ali, Daubin, Vincent, Arvestad, Lars, Sennblad, Bengt, Lagergren, Jens   +5 more
openaire   +3 more sources

Studies on plant gene transfer systems [PDF]

, 1989
A number of methods for the transfer of genes to plants are assessed in this work. The potential of Agrobacterium tumefaciens infection of germinating pollen tubes in vitro as a method of gene transfer was investigated and evidence presented for an ...
Sherman, Adrian
core  

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms

Frontiers in Cellular and Infection Microbiology, 2012
Based on Darwin’s concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions and duplication were streaming the genomes of living organisms.
Claire eBertelli, Gilbert eGreub
doaj   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

A complex and punctate distribution of three eukaryotic genes derived by lateral gene transfer

BMC Evolutionary Biology, 2007
Background Lateral gene transfer is increasingly invoked to explain phylogenetic results that conflict with our understanding of organismal relationships. In eukaryotes, the most common observation interpreted in this way is the appearance of a bacterial
Durnford Dion G, Harper James T, Watkins Russell F, Rogers Matthew B, Gray Michael W, Keeling Patrick J   +5 more
doaj   +1 more source

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

Advanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy, Kyle B. Meerbott, Lorenzo Travaglini, Garima S. Dobhal, Artur Sawicki, Marc R. Knecht, Tiffany R. Walsh, Dominic J. Glover   +7 more
wiley   +1 more source

Adaptations to High Salt in a Halophilic Protist: Differential Expression and Gene Acquisitions through Duplications and Gene Transfers

Frontiers in Microbiology, 2017
The capacity of halophiles to thrive in extreme hypersaline habitats derives partly from the tight regulation of ion homeostasis, the salt-dependent adjustment of plasma membrane fluidity, and the increased capability to manage oxidative stress ...
Tommy Harding, Andrew J. Roger, Alastair G. B. Simpson   +2 more
doaj   +1 more source

Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. [PDF]

PLoS Computational Biology, 2013
There are 10× more bacterial cells in our bodies from the microbiome than human cells. Viral DNA is known to integrate in the human genome, but the integration of bacterial DNA has not been described. Using publicly available sequence data from the human
David R Riley, Karsten B Sieber, Kelly M Robinson, James Robert White, Ashwinkumar Ganesan, Syrus Nourbakhsh, Julie C Dunning Hotopp   +6 more
doaj   +1 more source