Results 61 to 70 of about 10,354,524 (352)

Research on nonlinear modeling and dynamic characteristics of lateral stiffness of vehicle air spring system

Advances in Mechanical Engineering, 2020
This paper established a lateral stiffness coupling model to investigate the lateral characteristics of air spring system under crosswind conditions.
Liufeng Xu
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Investigation of normal, lateral, and oblique impact of microscale projectiles into unidirectional glass/epoxy composites

Defence Technology, 2022
Spacesuits and spacecraft must endure high velocity impacts from micrometeoroids. This work considers the impact of 100 μm diameter projectiles into composite targets at velocities from 0.5 km/s to 2 km/s.
Christopher S. Meyer, Isabel G. Catugas, John W. Gillespie, Jr., Bazle Z. Gama Haque   +3 more
doaj   +1 more source

Chirality in Quantum Computation with Spin Cluster Qubits

, 2004
We study corrections to the Heisenberg interaction between several lateral, single-electron quantum dots. We show, using exact diagonalization, that three-body chiral terms couple triangular configurations to external sources of flux rather strongly. The
C. G. Darwin, K. Park, M. V. Berry, S. Das Sarma, V. Fock, V. W. Scarola   +5 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Assessment of Force-Deflection Relations of Steel Tubular Members under Lateral Quasi-Static Impacts from Dropped Objects

نشریه مهندسی دریا, 2015
In the current study a numerical simulation approach has been chosen to simulate the force-deflection response of tubular member under lateral impact in the absence of internal pressure or axial force and the results have then been compared with ...
Mehdi Ezzati, Mostafa Zeinoddini, Tahereh Masoudi   +2 more
doaj  

Dynamic analysis of debris flow impact on double-column bridge piers based on SPH-FEM coupling

Shenzhen Daxue xuebao. Ligong ban
Based on the smoothed particle hydrodynamics-finite element method (SPH-FEM), a dynamic interaction model of debris flow, comprising both slurry and boulders as well as impacting a double-column bridge pier, is constructed to study the dynamic response ...
LU Yuchun, HAO Mengjie, ZHAO Debo, LIU Bin, HAN Yugang, HE Liang   +5 more
doaj   +1 more source

Electronic Transport and Thermopower in 2D and 3D Heterostructures--A Theory Perspective

, 2019
In this review, we discuss the impact of interfaces and heterojuctions on the electronic and thermoelectric transport properties of materials. We review recent progress in understanding electronic transport in two-dimensional (2D) materials ranging from ...
Aksamija, Zlatan, Kommini, Adithya, Majee, Arnab K.   +2 more
core   +1 more source

Lateral stress evolution in chromium sulfide cermets with varying excess chromium [PDF]

, 2016
The shock response of chromium sulfide-chromium, a cermet of potential interest as a matrix material for ballistic applications, has been investigated at two molar ratios.
Appleby-Thomas, Gareth J., Capozzi, A., Frost, D. L., Goroshin, S., Hazell, P. J., Nabavi, Seyed Ali, Petel, O. E., Wood, D. C.   +7 more
core   +1 more source