Results 61 to 70 of about 1,810,032 (168)

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, Volume 13, Issue 53, 24 September 2026.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

A Novel Lumbar Motion Segment Classification to Predict Changes in Segmental Sagittal Alignment After Lateral Interbody Fixation

Global Spine Journal, 2017
Study Design: Retrospective cohort study. Objectives: Lateral interbody fixation is being increasingly used for the correction of segmental sagittal parameters.
Frank L. Acosta MD, Vivek A. Mehta MD, Anush Arakelyan MPH, Doniel Drazin MD, Clarissa Cortland BA, Patrick C. Hsieh MD, John C. Liu MD, Martin H. Pham MD   +7 more
doaj   +1 more source

Minimally invasive direct lateral interbody fusion in the treatment of the thoracic and lumbar spinal tuberculosisMini-DLIF for the thoracic and lumbar spinal tuberculosis

BMC Musculoskeletal Disorders, 2018
Background To investigate the clinical efficacy of minimally invasive direct lateral approach debridement, interbody bone grafting, and interbody fusion in the treatment of the thoracic and lumbar spinal tuberculosis. Methods From January 2013 to January
Fengping Gan, Jianzhong Jiang, Zhaolin Xie, Shengbin Huang, Ying Li, Guoping Chen, Haitao Tan   +6 more
doaj   +1 more source

Are Ceramic Cages an Option for Lumbar Interbody Fusion? A Comparative Biomechanical Numerical Study

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The treatment of severe disc pathologies through lumbar interbody fusion (LIF) involves the insertion of an interbody cage into the degenerated disc space, together with a supporting fixation system. Conventional cage materials, such as Ti6Al4V and PEEK, present several limitations, most notably their non‐biodegradability ...
Davide Ninarello, Luigi La Barbera
wiley   +1 more source

Is Direct Decompression Necessary for Lateral Lumbar Interbody Fusion (LLIF)? A Randomized Controlled Trial Comparing Direct and Indirect Decompression With LLIF in Selected Patients [PDF]

Neurospine
Objective To compare the clinical and radiographic outcomes following lateral lumbar interbody fusion (LLIF) between direct and indirect decompression in the treatment of patients with degenerative lumbar diseases.
Worawat Limthongkul, Chayapong Thanapura, Khanathip Jitpakdee, Pakawas Praisarnti, Vit Kotheeranurak, Wicharn Yingsakmongkol, Teerachat Tanasansomboon, Weerasak Singhatanadgige   +7 more
doaj   +1 more source

Efficacy and radiographic analysis of oblique lumbar interbody fusion in treating adult spinal deformity.

PLoS ONE, 2021
Adult spinal deformity (ASD) is usually rigid and requires a combined anterior-posterior approach for deformity correction. Anterior lumbar interbody fusion (ALIF) allows direct access to the disc space and placement of a large interbody graft.
Dae-Jean Jo, Eun-Min Seo
doaj   +1 more source

Safety and Stability of a Combined C2 Screw Placement Strategy With Vertebral Artery Mobilization

Orthopaedic Surgery, Volume 18, Issue 9, Page 1892-1903, September 2026.
An individualized C2 screw fixation strategy incorporating vertebral artery mobilization and atlantoaxial fusion cage support ensures safe, stable, and effective fixation in complex upper cervical anatomies, providing a reproducible approach for challenging craniovertebral junction reconstruction.
Peng Song, Shuangyin He, Tao Chen, Han Chen, Wenfu Yang, Xiyuan Tang, Tingting Xu, Xiaohong Yin, Bo Tan   +8 more
wiley   +1 more source

Clinical and Radiological Outcomes of Monosegmental Minimally Invasive Transforaminal Lumbar Interbody Fusion for High‐Grade Spondylolisthesis: A 3‐Year Observational Study

Orthopaedic Surgery, Volume 18, Issue 8, Page 1591-1600, August 2026.
In this study, we performed two approaches of MIS‐TLIF and percutaneous pedicle screw fixation to offer safe and effective treatment of high‐grade spondylolisthesis with satisfactory clinical and radiological outcomes. ABSTRACT Objective High‐grade isthmic spondylolisthesis remains surgically controversial, and evidence on minimally invasive, single ...
Chao Liu, Ya Wang, Changqing Li, Piming Nie   +3 more
wiley   +1 more source

A Comparative Study of Lateral Lumbar Interbody Fusion and Posterior Lumbar Interbody Fusion in Degenerative Lumbar Spondylolisthesis [PDF]

, 2015
Study DesignLevel 4 retrospective review.PurposeTo compare the radiographic and clinical outcomes between posterior lumbar interbody fusion (PLIF) and lateral lumbar interbody fusion (LLIF) with posterior segmental spinal instrumentation (SSI) for ...
Abhijit Y. Pawar, Frank P. Cammisa, Federico P. Girardi, Darren R. Lebl, Andrew A. Sama, Alexander P. Hughes   +5 more
core   +1 more source

Comparative Clinical and Radiological Outcomes of Arthroscopic‐Assisted Uniportal Spinal Surgery Versus Unilateral Biportal Endoscopy for Unilateral Laminotomy With Bilateral Decompression in Lumbar Spinal Stenosis: A 2‐Year Follow‐Up Study

Orthopaedic Surgery, Volume 18, Issue 8, Page 1613-1622, August 2026.
This study compares two minimally invasive techniques, arthroscopic‐assisted uniportal spinal surgery (AUSS) and unilateral biportal endoscopy (UBE), for treating lumbar spinal stenosis using unilateral laminotomy with bilateral decompression (ULBD). Over a 2‐year follow‐up, perioperative outcomes, patient‐reported improvement, and radiological changes,
Abdul Waheed Bahir, Wang Daxing, Liu Bailian, Gan Xuewen, Xiong Ying, Xiao Jiayu, Gu Shao   +6 more
wiley   +1 more source