Results 31 to 40 of about 3,250,455 (246)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Research on Optimal Arch Rib Inclination of Large Span Highway CFST through Arch Bridge

open access: yesBuildings, 2023
To investigate the reasonable range of the inclination angle of arch ribs, a spatial finite element method was employed based on a concrete-filled steel tube (CFST) basket-handle through an arch bridge with a span of 360 m. A spatial finite element model
Zengwu Liu   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and Development of an Innovative Two-Degree-of-Freedom Rear Suspension System for Reverse Trikes

open access: yesVehicles
This paper presents the research, development, and functional validation of an original rear suspension system designed for hybrid reverse trike vehicles (two guided wheels on the front axle and a twin-tire-driven assembly at the rear).
Mădălina Boțu   +4 more
doaj   +1 more source

Improved ADRC-Based Autonomous Vehicle Path-Tracking Control Study Considering Lateral Stability

open access: yesApplied Sciences, 2022
The antidisturbance control problem of autonomous vehicle path tracking considering lateral stability is studied in this paper. This paper proposes an improved active disturbance rejection control (IADRC) control method including an improved extended ...
Nan Kang, Yi Han, Tian Guan, Siyu Wang
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Postural stability when walking and exposed to lateral oscillations

open access: yes, 2012
The role of accelerations encountered in daily life in causing postural instability or falls is not well understood, especially when walking. Lateral oscillations disturb walking stability during train journeys but it is desirable that passengers feel ...
Sari, M.H.
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Stability of liquid bridges between twisted elliptical disks [PDF]

open access: yes, 2005
The influence in the stability of long liquid bridges supported between two elliptical-shaped disks of their main axis relative orientation is investigated.
Laverón Simavilla, Ana   +2 more
core   +1 more source

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