Results 121 to 130 of about 285,303 (312)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Periosteal flap augmentation of the Modified Broström–Gould procedure for chronic lateral ankle instability [PDF]

, 2018
Chee Ping Chew, Kevin Koo, Denny Lie
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Anatomical Considerations for the Use of the Popliteal Vein as a Potential Alternative for Central Venous Cannulation

Anatomia
Limited reports have evaluated the utility of the popliteal vein (PV) specific to cannulation. The objective of this study was to characterize the diameter and length of the PV to evaluate this area as a potential cannulation site.
Aaron L. Graves, Charles R. Marchese, Bradley A. Creamer, Jennifer F. Dennis   +3 more
doaj   +1 more source

Subependymomas of the lateral ventricle: Tumor recurrence correlated with increased Ki-67 labeling index [PDF]

, 2009
Maria Koutourousiou, Nikolaos Georgakoulias, George Kontogeorgos, Andreas Seretis   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Lateral thinking [PDF]

Current Biology, 1999
openaire   +2 more sources

C19-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities

, 2018
Qing‐Lan Guo, Huan Xia, Xian‐Hua Meng, Gaona Shi, Chengbo Xu, Chenggen Zhu, Tiantai Zhang, Jian‐Gong Shi   +7 more
openalex   +1 more source

Laterality of Skin Temperature Depending on Sensory Symptoms in Patient with Wallenberg Syndrome [PDF]

, 2021
Ji Eun Han, Sun Ki Min, Jinyoung Oh, Taemin Kim, Sang Won Han, Woo Yong Lee, Jong Sam Baik   +6 more
openalex   +1 more source