Results 121 to 130 of about 1,285,399 (346)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effect of biomechanical constraints in the hand laterality judgment task: where does it come from?

open access: yesFrontiers in Human Neuroscience, 2012
Several studies have reported that, when subjects have to judge the laterality of rotated hand drawings, their judgment is automatically influenced by the biomechanical constraints of the upper limbs.
G. Vannuscorps, Agnesa Pillon, M. Andres
semanticscholar   +1 more source

In praise of ambidexterity: How a continuum of handedness predicts social adjustment [PDF]

open access: yes
This paper estimates the relationship between handedness and social adjustment. In addition to binary measures of hand preference, we also use a continuous measure of hand skill. Outcomes at ages 7, 11 and 16 are studied.
Kevin Denny, Wen Zhang
core   +3 more sources

Comparing Generalized and Social Anxiety Disorders Between Sinistral and Dextral Children With Depression Symptoms

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2019
Background and Aim There is a high correlation between depression and anxiety in children which are also related to laterality. This study aimed to compare generalized anxiety and social anxiety in sinistral and dextral children with depression symptoms. 
Tooraj Sepahvand, Jalil Moradi
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Laterality [PDF]

open access: yesJournal of Bodywork and Movement Therapies, 2011
openaire   +3 more sources

An aspect of the Japanese language in relation to dyslexia : a thesis presented in partial fulfilment of the requirement for the degree of Master of Arts in Japanese at Massey University [PDF]

open access: yes, 1987
These studies were conducted to examine the processing of two kinds of Japanese orthography, namely, kanji and hiragana by a group of dyslexic Subjects and Subjects in a control group of similar age, in order to ascertain the effectiveness of hemispheric
Roberts, Joan Gladys
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Cognitive Ability and Hemispheric Indecision - Two Surpluses and a Deficit [PDF]

open access: yes
This paper re-examines a finding by Crow et al. (1998) showing that equal skill of right and left hands – hemispheric indecision - is associated with deficits in cognitive ability. This is consistent with the idea that failure to develop dominance of one
Kevin Denny
core   +3 more sources

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