PERAN PEMERIKSAAN MRI DTI DAN MT DALAM MENDETEKSI SKLEROSIS HIPOKAMPUS PADA EPILEPSI LOBUS TEMPORALIS MESIAL INTRAKTABEL DENGAN MRI NORMAL [PDF]
Latar belakang : Etiologi Epilepsi Lobus Temporal Mesial (ELTM) intraktabel tersering adalah sklerosis hipokampus. Sekitar 20-30% pasien epilepsi fokal intraktabel menunjukkan MRI standar normal.MRI DTI dan MT, mempunyai kemampuan menunjukkan substrat ...
SUKMANINGTYAS, Hermina
core
Brain lesion volume and capacity for consent in stroke trials: potential regulatory barriers to the use of surrogate markers [PDF]
<p><b>Background and Purpose:</b> European directives and legislation in some countries forbid inclusion of subjects incapable of consent in research if recruitment of patients capable of consent will yield similar results.
Dani, K.A., McCormick, M.T., Muir, K.W.
core +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Anterior Prefrontal Cortex Contributes to Action Selection through Tracking of Recent Reward Trends [PDF]
The functions of prefrontal cortex remain enigmatic, especially for its anterior sectors, putatively ranging from planning to self-initiated behavior, social cognition, task switching, and memory.
Adolphs, Ralph +5 more
core
One Action System or Two? Evidence for Common Central Preparatory Mechanisms in Voluntary and Stimulus-Driven Actions [PDF]
Human behavior is comprised of an interaction between intentionally driven actions and reactions to changes in the environment. Existing data are equivocal concerning the question of whether these two action systems are independent, involve different ...
Hughes, G, Schutz-Bosbach, S, Waszak, F
core +3 more sources
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Background/Objectives: Functional MRI (fMRI) is widely used to assess language lateralization, but its application in patients with brain tumors can be hindered by cognitive impairments, compensatory neuroplasticity, and artifacts due to patient movement
Daniel Solomons +5 more
doaj +1 more source
Most language functions are under the dominance of the left cerebral hemisphere and involve a complex neural network in which some cerebral regions play a key-role such as Broca’s and Wernicke's areas within the frontal and the temporal lobes ...
Adrien Meguerditchian +3 more
doaj +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

