Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats
In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem +18 more
wiley +1 more source
Pregnancy identification method as a source of bias in studies of prenatal exposures using real-world data. [PDF]
Latour CD +5 more
europepmc +1 more source
ABSTRACT Background Teacher agency plays a pivotal role in technology‐enhanced instruction, yet empirical evidence connecting agency to the practical enactment of specific components of TPACK remains limited. In particular, the intersections between teacher agency and TPK/TCK as enacted practices warrant closer scrutiny.
Hyojoon Kim, Eun‐Jeong Yu
wiley +1 more source
Indirect treatment comparison of iptacopan versus pegcetacoplan for patients with paroxysmal nocturnal hemoglobinuria and residual anemia despite C5 inhibitor treatment. [PDF]
Kulasekararaj A +9 more
europepmc +1 more source
Drawing teaching into scorable form: A socio‐material critique of lesson observation
Abstract Amid rising accountability and standardisation mandates, paraprofessional educators constitute a growing yet precarious segment of the global education workforce. While their roles are expanding, the instruments used to assess their practice remain critically underexamined, despite having significant consequences for professional identity and ...
Elizabeth Hashimura, Rob McGregor
wiley +1 more source
A phase I/II trial of concurrent chemo-hormonal enzalutamide and cabazitaxel in patients with metastatic castration-resistant prostate cancer. [PDF]
Graff JN +14 more
europepmc +1 more source
ABSTRACT Stable isotope analysis (SIA) provides essential information toward a better understanding of trophic ecology. However, the interpretation of SIA results relies on assumptions about the trophic discrimination factor (TDF), which aims to improve the accuracy but may lead to bias.
I. Kuklina +6 more
wiley +1 more source
A feasibility randomised controlled trial of an exergaming device aimed at improving mobility in children with cerebral palsy. [PDF]
Rapson R +5 more
europepmc +1 more source
Fraying the Edges of Literacies: What Do Post‐Philosophies Produce for Early Childhood Literacies?
Paper skateboard park and worms' house; is it literacy? We invite a discussion on how post‐philosophies have, and could, open up possibilities for thinking about early literacies. By fraying the edges of certainty and legitimacy around what counts as literacy and who is viewed as literate (according to humanist logics), post‐philosophical concepts ...
Abigail Hackett, Candace R. Kuby
wiley +1 more source
Persistent genital arousal symptoms in a young woman with recurring brief psychoses: a clinical dilemma in antipsychotic choice. [PDF]
Fortin-Latour É, Stip E.
europepmc +1 more source

