Results 31 to 40 of about 165,566 (309)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Law and Economics in Australia

open access: yesLegal Education Review, 1989
The difficulty of talking compendiously about law and economics should not be underestimated. I have witnessed various attempts in the past, and they have usually failed. The presenter tends to make one of two mistakes. The first is to concentrate on the
Anthony Duggan
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Behavioural Law and Economics as Litmus Test

open access: yesŒconomia, 2017
This paper discusses a few meta-theoretical questions about Behavioural Law and Economics (BLE) in order to better understand both its popularity and the criticisms it has received.
Péter Cserne
doaj   +1 more source

Connections and interference between Law & Economics and Comparative Law

open access: yes, 2023
openDiritto comparato e Law & Economics condividono nella loro essenza la volontà di non rassegnarsi a vedere il diritto in un ottica formalista e positivista, dirigendo piuttosto la ricerca verso una multidisciplinarità che si rivela uno strumento ...
DONO', ALESSANDRO
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

TRANSCONSTITUCIONALISMO: RACIONALIDADE TRANSVERSAL E LAW & ECONOMICS

open access: yesRevista Eletrônica Direito e Política, 2014
Este artigo tem por objeto a aproximação com a teoria dos sistemas para identificar, no plano reflexivo da estrutura normativa, o fenômeno do Transconstitucionalismo, especialmente o “comércio” entre juízes mediante a análise da racionalidade ...
Mauricio Salvadori Carvalho de Oliveira
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

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