Results 31 to 40 of about 3,228,812 (333)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Responsibility of monks in the context of law and society [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2020
In the course of history, ecclesiastical life has been imbued by secular beliefs, embodied in human endeavour to get a strong foothold in the Church. Since Emperor Constantine's era, the idea that matured in the ecclesiastical consciousness was that the ...
Gligić Sanja
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

INTERNATIONAL LAW IN THE CONTEXT OF ECONOMIC GLOBALIZATION

open access: yesRUDN Journal of Law, 2019
The article examines the international legal integration regulation of relations in the sphere of economics and finance context of globalization. The modern era - an era of globalization, which includes the highly dynamic development of integration ...
Andrey A. Mamedov, Vera N. Batova
doaj   +1 more source

“One Size Can Fit All” – On the Mass Production of Legal Transplants [PDF]

open access: yes, 2013
Law reformers like the World Bank sometimes suggest that optimal legal rules and institutions can be recognized and then be recommended for law reform in every country in the world. Comparative lawyers have long been skeptical of such views.
Michaels, Ralf
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Law Enforcement in the Context of Legal Culture in Society

open access: yesLaw Reform: Jurnal Pembaharuan Hukum, 2020
Law enforcement is a series of processes to describe values, ideas, ideals, and subsequently become legal objectives. The awareness and compliance of sailing administration to Matras fishermen in catching fish is very much determined by the legal culture
Derita Prapti Rahayu   +3 more
doaj   +1 more source

Pragmatic Administrative Law and Tax Exceptionalism [PDF]

open access: yes, 2014
This Essay responds to the 2014 Duke Law Journal Administrative Law Symposium. Its principal contention is that courts and other commentators should give due weight to the history and virtues of the evolution of administrative law in the United States ...
Murphy, Richard
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

TREASON IN THE CONTEXT OF INDONESIAN CRIMINAL LAW

open access: yesHamdard Islamicus, 2020
Indonesian criminal law addresses treason in its Penal Code. Since the ruling regime frequently uses the Penal Code articles to criminalize political opponents or members of opposition groups, the articles are interpreted broadly by both prosecutors and
Sofian, A, Faradila, A, Fitriasih, S.
doaj   +2 more sources

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