Results 31 to 40 of about 3,112,779 (283)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
INTERNATIONAL LAW IN THE CONTEXT OF ECONOMIC GLOBALIZATION
RUDN Journal of Law, 2019 The article examines the international legal integration regulation of relations in the sphere of economics and finance context of globalization. The modern era - an era of globalization, which includes the highly dynamic development of integration ...
Andrey A. Mamedov, Vera N. Batova
doaj +1 more source
Responsibility of monks in the context of law and society [PDF]
Zbornik Radova Pravnog Fakulteta u Nišu, 2020 In the course of history, ecclesiastical life has been imbued by secular beliefs, embodied in human endeavour to get a strong foothold in the Church. Since Emperor Constantine's era, the idea that matured in the ecclesiastical consciousness was that the ...
Gligić Sanja
doaj +1 more source
“One Size Can Fit All” – On the Mass Production of Legal Transplants [PDF]
, 2013 Law reformers like the World Bank sometimes suggest that optimal legal rules and institutions can be recognized and then be recommended for law reform in every country in the world. Comparative lawyers have long been skeptical of such views.
Michaels, Ralf
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Pragmatic Administrative Law and Tax Exceptionalism [PDF]
, 2014 This Essay responds to the 2014 Duke Law Journal Administrative Law Symposium. Its principal contention is that courts and other commentators should give due weight to the history and virtues of the evolution of administrative law in the United States ...
Murphy, Richard
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
TREASON IN THE CONTEXT OF INDONESIAN CRIMINAL LAW
Hamdard Islamicus, 2020 Indonesian criminal law addresses treason in its Penal Code. Since the ruling regime frequently uses the Penal Code articles to criminalize political opponents or members of opposition groups, the articles are interpreted broadly by both prosecutors and
Sofian, A, Faradila, A, Fitriasih, S.
doaj +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source