Results 41 to 50 of about 44,063 (259)

Atlas cartographiques du droit de l’environnement marin en Afrique de l’Ouest. Méthodologie et usage pour la planification spatiale

open access: yesCybergeo, 2020
In the marine environment, positive law generates multiple zones and regulatory limits that overlap in space, justifying a cartographic representation as a relevant approach to promote understanding (synthetic vision), analysis (highlighting legal ...
Matthieu Le Tixerant   +10 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Donald R Rothwell & Tim Stephens, The International Law of the Sea (London: Bloomsbury, 2016, 2nd ed.)

open access: yesNordicum-Mediterraneum, 2017
A review of the book: Donald R Rothwell and Tim Stephens, The International Law of the Sea (London: Bloomsbury, 2016, 2nd ed.), pp. 553 & xlviii, 36 GBP (paperback); 25.99 GBP (kindle ebook), ISBN: 9781782256849 (paperback).
Rachael L. Johnstone
doaj  

Participation as the Essence of Good Governance: Some General Reflections and a Case Study on the Arctic Council

open access: yesArctic Review on Law and Politics, 2017
The present contribution explores aspects of good governance on the global dimension with participation as one of the key elements of a well-governed system, focusing on the Arctic Council’s (AC) commitment to enhance indigenous peoples’ participation in
Margherita Paola Poto, Lara Fornabaio
doaj   +1 more source

SOUTH CHINA SEA: CONFLICT, CHALLENGE, AND SOLUTION

open access: yesLampung Journal of International Law, 2021
The South China Sea is a strategic marine area in terms of natural resource potential and international trade routes. For decades, territorial disputes have occurred with peaceful solutions from regional organizations, international courts, and even ...
Winanda kusuma   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Key Moments of Development and Present Face of International Law of the Sea [PDF]

open access: yesSocietas et Iurisprudentia, 2016
International law of the sea can be defined as a body of law governing regime of the seas and regulating relations between subjects of international law in connection with their activities on the seas and oceans in the world.
Juraj Jankuv
doaj  

Conservation and Sustainable Use of Arctic Marine Biodiversity:

open access: yesArctic Review on Law and Politics, 2010
The status of the marine Arctic as ‘the last wilderness’ may be challenged in future by increased activities provided by the melting of the sea ice. The fragile ecosystems and habitats may come under threat.
Tore Henriksen
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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