Results 41 to 50 of about 603,795 (280)

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

The Role of Temporal and Spectral Cues in Non-native Speech Production:

Crossings, 2023
This study investigated the role of durational and spectral cues in second language tense and lax vowel contrasts produced by non-native speakers. To test previous claims that speakers primarily rely on durational cues over spectral cues to distinguish ...
Md. Jahurul Islam, Abdulla Al Masum Abdulla Al Masum, Md. Sayeed Anwar   +2 more
doaj  

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

Darboux covariant Lax pairs and infinite conservation laws of the (2+1)-dimensional breaking soliton equation [PDF]

, 2011
In this paper, the binary Bell polynomials are applied to succinctly construct bilinear formulism, bilinear Bäcklund transformations, Lax pairs, and Darboux covariant Lax pairs for the (2+1)-dimensional breaking soliton equation.
Fan, E, Kwok Wing Chow, Engui Fan, Chow, KW   +3 more
core   +1 more source

Geometry of coupled dispersionless equations with Mannheim curves

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2023
In this paper, a special kind of curve pair associated with each other by the linear dependency between the principal normal vector of the first curve (called Mannheim curve) and the binormal vector of the second curve (called Mannheim partner curve) is ...
Eren Kemal
doaj   +1 more source

Musculoskeletal Phenotypes of 19 Patients With X‐Linked HNRNPH2‐Related Neurodevelopmental Disorder: A Prospective Case Series

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Detailed clinical phenotypes have been previously reported for 33 individuals with X‐linked HNRNPH2‐related neurodevelopmental disorder. Of these, 75% self‐reported a musculoskeletal abnormality, including hip dysplasia, scoliosis, kyphosis, lordosis, pes planus, arthritis, and missing spinous processes.
Ambar Garcia, Rachel Salazar, Nicole Holuba, Franklin E. Paulino, Michael G. Vitale, Jennifer M. Bain, Joshua Hyman   +6 more
wiley   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

Pelvic morphology and body size in relation to the preauricular sulcus: Evidence from medieval to modern Iberia

The Anatomical Record, EarlyView.
Abstract The preauricular sulcus has long been debated as a pelvic feature variably attributed to obstetric stress, ligamentous traction, and broader biomechanical processes. To clarify its determinants, we analyzed 409 adult individuals from three archeological and one early modern skeletal collection from the Iberian Peninsula, integrating graded ...
Rebeca García‐González, Julia Muñoz‐Guarinos, Nico Cirotto, Sonia Díaz‐Navarro, Laura Rodríguez, José Miguel Carretero   +5 more
wiley   +1 more source

Soliton Solutions to Sasa–Satsuma-Type Modified Korteweg–De Vries Equations by Binary Darboux Transformations

Mathematics
Sasa–Satsuma (SS)-type integrable matrix modified Korteweg–de Vries (mKdV) equations are derived from two group constraints, involving the replacement of the spectral matrix in the Ablowitz–Kaup–Newell–Segur matrix eigenproblems with its matrix transpose
Wen-Xiu Ma
doaj   +1 more source

Weak Lax pairs for lattice equations [PDF]

Nonlinearity, 2012
We consider various 2D lattice equations and their integrability, from the point of view of 3D consistency, Lax pairs and Bäcklund transformations. We show that these concepts, which are associated with integrability, are not strictly equivalent. In the course of our analysis, we introduce a number of black and white lattice models, as well as variants
Hietarinta, Jarmo, Viallet, Claude
openaire   +4 more sources