A clinical decision support alert to promote timely laxative use in in-patients prescribed clozapine [PDF]
Background Clozapine-induced gastrointestinal hypomotility and constipation can result in severe and sometimes fatal gastrointestinal complications.
Milan Sundermann+3 more
doaj +2 more sources
Effectiveness of laxatives in adults [PDF]
This paper summarises the research evidence presented in a recent issue of Effective Health Care on the effectiveness of the four main types of laxatives used in the treatment of constipation in adults.1 The bulletin was based on two systematic reviews2,3 (table 1) and on the additional randomised controlled trials (RCTs) identified since the ...
M Petticrew
+6 more sources
The impact of laxative use upon symptoms in patients with proven slow transit constipation [PDF]
Background Constipation severity is often defined by symptoms including feelings of complete evacuation, straining, stool frequency and consistency. These descriptors are mostly obtained in the absence of laxative use.
Dinning Phil G+5 more
doaj +5 more sources
Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells [PDF]
OBJECTIVE: Polyethylene glycol (PEG), an osmotic laxative, is a potent inhibitor of colon cancer in rats. In a search for the underling mechanisms, the hypothesis that fecal bulking and moisture decrease colon carcinogenesis was tested.
Sylviane Taché+3 more
openalex +5 more sources
Comparison of Efficacies of a Blonanserin Transdermal Patch and Blonanserin Oral Formulation for Psychiatric Symptoms in Patients With Schizophrenia Treated With Laxatives Using a Japanese Claims Database [PDF]
Background Laxative use has recently been indicated as a risk factor for hospitalization in patients with schizophrenia. Oral antipsychotic therapy for patients with schizophrenia treated with laxatives may be problematic due to gastrointestinal ...
Ken Inada+7 more
doaj +2 more sources
The association between benzodiazepine prescriptions and the risk of laxative use in schizophrenia treatment [PDF]
Aim Constipation is one of the most common adverse effects in schizophrenia treatment, and it can sometimes cause severe gastrointestinal disease. However, the results of association studies between constipation and psychotropic medications in patients ...
Shinichiro Ochi+14 more
doaj +2 more sources
Pivotal role of venous blood gas analysis in the detection of metabolic acidosis due to laxative abuse in an anorexia nervosa patient: A case report [PDF]
Background Anorexia nervosa has the highest mortality rate of any psychiatric disorder, and purging behaviors can cause a fatal electrolyte and acid–base imbalance.
Satoshi Miwa+2 more
doaj +2 more sources
Factors associated with the initiation of laxative use in the same patients with schizophrenia over a 20‐year period: Retrospective cohort study [PDF]
Background Constipation is a common adverse effect of antipsychotics, but little investigation has been conducted. We aimed to address the factors associated with the initiation of laxative use in the same patients with schizophrenia over a 20‐year ...
Yasushi Kawamata+13 more
doaj +2 more sources
The Detection of Laxative Abuse [PDF]
John Morton
openalex +4 more sources
We define a Lax operator as a monic pseudodifferential operator $L(\partial)$ of order $N\geq 1$, such that the Lax equations $\dfrac{\partial L(\partial)}{\partial t_k}=[(L^{\frac kN}(\partial))_+,L(\partial)]$ are consistent and non-zero for infinitely many positive integers $k$.
De Sole A., Kac V. G., Valeri D.
openaire +2 more sources