Results 11 to 20 of about 83,789 (365)

Laxative Use in the Community: A Literature Review [PDF]

Journal of Clinical Medicine, 2021
Laxatives are widely available without prescription and, as a consequence, they are commonly used for self-management of constipation by community-dwelling adults. However, it is not clear to what extent laxatives are used.
Barry Werth, Sybèle-Anne Christopher
openalex   +2 more sources

Association Between Regular Laxative Use and Incident Dementia in UK Biobank Participants

Neurology, 2023
Background and Objectives The use of over-the-counter laxatives is common in the general population. The microbiome-gut-brain axis hypothesis suggests that the use of laxatives could be associated with dementia.
Zhirong Yang, Chang Wei, Xiaojuan Li, Jinqiu Yuan, Xuefeng Gao, Bingyu Li, Zi-Yi Zhao, S. Toh, Xin Yu, C. Brayne, Zuyao Yang, F. Sha, Jinling Tang   +12 more
semanticscholar   +1 more source

Based on Network Pharmacology and Gut Microbiota Analysis to Investigate the Mechanism of the Laxative Effect of Pterostilbene on Loperamide-Induced Slow Transit Constipation in Mice

Frontiers in Pharmacology, 2022
Background: Pterostilbene (PTE) is a natural polyphenol compound that has been proven to improve intestinal inflammation, but its laxative effect on slow transit constipation (STC) has never been studied.
Zhiwei Yao, Siqi Fu, Bingbing Ren, Lushun Ma, Daqing Sun   +4 more
semanticscholar   +1 more source

Antioxidant activity and laxative effects of tannin-enriched extract of Ecklonia cava in loperamide-induced constipation of SD rats

PLoS ONE, 2021
To investigate the role of tannin-enriched extracts of Ecklonia cava (TEE) on the regulation of oxidative balance and laxative activity in chronic constipation, we investigated alterations after exposure to TEE, on constipation phenotypes, muscarinic ...
J. Kim, Y. Choi, Su Jin Lee, J. Gong, Young Ju Lee, J. Sung, Young-Suk Jung, H. Lee, J. Hong, D. Hwang   +9 more
semanticscholar   +1 more source

Laxative Use and Risk of Dyskalemia in Patients with Advanced CKD Transitioning to Dialysis.

Journal of the American Society of Nephrology, 2021
BACKGROUND Patients with advanced CKD experience increased intestinal potassium excretion. This compensatory mechanism may be enhanced by laxative use; however, little is known about the association of laxative use with risk of dyskalemia in advanced CKD.
K. Sumida, Ankur A. Dashputre, P. Potukuchi, Fridtjof Thomas, Y. Obi, M. Molnar, J. Gatwood, E. Streja, K. Kalantar-Zadeh, C. Kovesdy   +9 more
semanticscholar   +1 more source

An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance

bioRxiv, 2021
Diarrheal samples from patients taking laxatives are typically rejected for Clostridioides difficile testing. However, there are similarities between the bacterial communities from people with diarrhea and those with C.
Sarah Tomkovich, Ana Taylor, Jacob King, Joanna Colovas, Lucas Bishop, K. McBride, Sonya Royzenblat, Nicholas A. Lesniak, I. Bergin, P. Schloss   +9 more
semanticscholar   +1 more source

Laxative effect of bitter almond (Amygdalus communis var. amara) [PDF]

The Iranian Journal of Veterinary Science and Technology, 2014
Thepossible laxative and prokinetic effects of bitter almond were studied: 1- two groups of 7 rats were gavaged with ethanol extract of bitter almond (500mg/kg) or placebo and the number of feces, fecal weight and its percentage of water were studied 18 ...
Hamid Reza Kazrani, Seddigheh Jalali
doaj   +1 more source

Treatment Experience of 210 Pediatric Patients With Extraordinary Daytime Urinary Frequency: A Prospective Study

Frontiers in Pediatrics, 2021
Background: Lactulose can be used to manage chronic constipation and children who are withholding their bowel movements, but no studies are available regarding lactulose to treat pediatric extraordinary daytime urinary frequency (PEDUF).
Yan Li, Ying Zhang, Chao Liu, Xiang Li, Qi Zhou, Chao Sun, Lei Zhang   +6 more
doaj   +1 more source

Laxative use and mortality in patients on haemodialysis: a prospective cohort study

BMC Nephrology, 2021
Background Patients on haemodialysis (HD) are often constipated. This study aimed to assess the relationship between constipation and mortality in such patients.
Yumiko Honda, S. Itano, Aiko Kugimiya, E. Kubo, Yosuke Yamada, Miho Kimachi, Y. Shibagaki, T. Ikenoue   +7 more
semanticscholar   +1 more source

Laxatives do not improve symptoms of opioid-induced constipation: results of a patient survey [PDF]

, 2017
Introduction: Laxatives are commonly used to treat opioid-induced constipation, the commonest and most bothersome complication of opioids. However, laxatives have a non-specific action and do not target underlying mechanisms of opioid-induced ...
Emmanuel, Anton, Johnson, Martin, McSkimming, Paula   +2 more
core   +4 more sources