Results 111 to 120 of about 283,067 (310)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Spartan Daily, March 28, 1938 [PDF]
Volume 26, Issue 106https://scholarworks.sjsu.edu/spartandaily/2743/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Córdoba is the first province of Argentina to adopt lay participation for the decision of criminal cases. Since 2005, a mixed tribunal of 8 lays and 3 judges decide some criminal cases by the rule of majority.
Santiago Abel Amietta
doaj
Military Courts as a Tool in the Polish Workers’ Party’s Fight for Power (1944–1948)
The paper is an attempt to answer the following questions: How did the tasks of pro tecting the political system and elimination of political enemies determine the structure and organisation of the military courts?
Marta Paszek
doaj +1 more source
What Discourages Participation in the Lay Judge System (Saiban’in Seido) of Japan? Interaction between the Secrecy Requirement and Social Networks. [PDF]
The lay judge system, a quasi-jury system, was introduced in Japan from May 2009. This paper attempts to analyze Japanese people’s attitude towards this system by examining whether they show a willingness to serve as a lay judge.
Yamamura, Eiji
core +1 more source
Landowners' liability? is perception of the risk of liability for visitors accidents a barrier to countryside access? [PDF]
The study seeks to analyse both the perception and reality of liability risk for owners of countryside land for injuries suffered by recreational visitors.
Bennett, L., Crowe, Lynn
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

