Results 141 to 150 of about 2,376,958 (329)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Participation of the Lay Christian Faithful in the Potestas Regiminis of the Catholic Church

open access: yesKościół i Prawo, 2013
This article analyses the contemporary canonical-legal situation of lays in the relation to the execution of the Church power of governance. It undertakes this question on the field of executive after the position of the laity in some special cases.
Monika Menke
doaj  

Promoting Informed Decision-Making: The Role of Message Structure [PDF]

open access: yes, 1999
The authors analyze two empirical explorations of relationships between the composition of risk message and critical thinking within ...
Juanillo, Napoleon, Jr.   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Five Year Cumulative Index: Articles and Comments by Title [PDF]

open access: yes, 1994
A five year cumulative index of articles and comments by title for the journal ...
RISK Editorial Board
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Capital Punishment without Capital Trials in Japan’s Lay Judge System

open access: yesAsia-Pacific Journal, 2010
In May 2009, Japan began a new trial system in which ordinary citizens sit with professional judges in order to adjudicate guilt and determine sentence in serious criminal cases.
David T. Johnson
doaj  

Competencia de los laicos en ética conyugal. Una brecha que se abre [PDF]

open access: yes, 2009
The article entitled «The competence of the laity in conjugal ethics. A breach that opens up...» attempts to be a reflection on the responsibility of married lay men and women in marriage matters. The primitive Church recognized the capacity of the laity
Botero, José Silvio
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy