Results 181 to 190 of about 128,206 (299)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Lay descriptions of painful temporomandibular disorders-an international consensus proposal for Global Burden of Disease estimates. [PDF]

BMC Med
Lövgren A, Liv P, Allison JR, Baad-Hansen L, Beecroft EV, Bergman S, Bijelic T, Bucci R, Böthun A, Christidis N, Colonna A, Draghici R, Drangsholt M, Durham J, Ernberg M, Giannakopoulos NN, Gonçalves DAG, Groenke B, Jusakos M, Lobbezoo F, Lua ESP, Lunecke G, Malysa A, Manfredini D, Marpaung C, Michelotti A, Moana-Filho E, Moreno B, Nilsson E, Nixdorf DR, Nykänen L, Oyarzo JF, Peck CC, Penlington C, Restrepo C, Rongo R, Schierz O, Stanisic N, Visscher CM, Wieckiewicz M, Xiong X, Xu YY, Yanez C, Häggman-Henrikson B, Svensson P.   +44 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Promoting community engagement in type 2 diabetes management: a systematic review and meta-analysis of community-based participatory research interventions. [PDF]

BMC Public Health
Ko G, Song Y.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Feasibility and acceptability of lay counsellor-delivered single-session therapy: a pragmatic mixed-methods pilot cohort study protocol. [PDF]

BMJ Open
Shava BK, Dambi J, Mushonga RH, Takaona T, Dzapasi L, Mashunye T, Mukoki CM, Tumbare E, Verhey R, Chibanda D.   +9 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Mid- and late-life depression increases risk of Alzheimer's disease and related dementias in veterans. [PDF]

Alzheimers Dement (Amst)
Kodama L, Valocchi E, Chanfreau-Coffinier C, Merritt VC.   +3 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Comparing Large Language Models and Traditional Machine Translation Tools for Translating Medical Consultation Summaries: Quantitative Pilot Feasibility Study. [PDF]

JMIR Form Res
Li A, Zhou W, Hoda R, Bain C, Poon P.
europepmc   +1 more source