Results 91 to 100 of about 902 (216)
四川大学学报. 自然科学版In an effort to investigate the effect of structural characteristics on the anisotropic mechanical properties and fracture evolution characteristics of gently dipping layered rock masses，a multifaceted experimental study was executed.This experiment ...
ZHENG Chuan-Tian +2 more
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Compliant Pneumatic Feet with Real‐Time Stiffness Adaptation for Humanoid Locomotion
Advanced Robotics Research, EarlyView.A compliant pneumatic foot with real‐time variable stiffness enables humanoid robots to adapt to changing terrains. Using onboard vision and pressure control, the foot modulates stiffness within each gait cycle, reducing impact forces and improving balance. The design, cast in soft silicone with embedded air chambers and Kevlar wrapping, offers durable,
Irene Frizza +3 more
wiley +1 more source
Geohazard MechanicsDeep underground rocks exhibit significant layered heterogeneity due to geological evolution and sedimentation. Rock fracture toughness, as one of the important indicators of hydraulic crack propagation, also exhibits heterogeneous distribution. In order
Kairui Li +4 more
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Grip and Grasp: Lizard Claw Inspired Robotic Manipulators
Advanced Robotics Research, EarlyView.Our study identifies the most effective lizard claw shape for use as an end effector in a bioinspired robotic manipulator. By examining key geometric features and combining them into comparative indices, the Crotaphytus collaris claw is found to be the best fit.
Hyeon Lee +4 more
wiley +1 more source
Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots
Advanced Robotics Research, EarlyView.This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou +4 more
wiley +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy +4 more
wiley +1 more source
Case Studies in Thermal EngineeringThe long-term stability of the surrounding rock of geothermal wellbore traversing groundwater and layered rock formations is commonly influenced by the combined effects of thermal, hydraulic, and mechanical factors. In order to mitigate the collapse risk
Haopeng Jiang, Annan Jiang, Fu Zheng
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Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues
Advanced Science, EarlyView.Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak +6 more
wiley +1 more source