Line-Field Confocal Optical Coherence Tomography (LC-OCT) for Skin Imaging in Dermatology [PDF]
Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive optical imaging technique based on a combination of the principles of optical coherence tomography and reflectance confocal microscopy with line-field illumination, which can ...
Flora Latriglia +6 more
doaj +5 more sources
Line-Field Confocal Optical Coherence Tomography for the Diagnosis of Skin Carcinomas: Real-Life Data over Three Years [PDF]
Line-field confocal optical coherence tomography (LC-OCT) can help the clinical diagnosis of skin diseases. The present study aimed to evaluate the sensitivity, specificity, and diagnostic accuracy of LC-OCT for the diagnosis of the most frequent non ...
Carolina Donelli +8 more
doaj +3 more sources
Trichoscopy and LC-OCT findings in sonidegib-induced alopecia in patients with advanced basal cell carcinoma. [PDF]
Sonidegib is a Hedgehog pathway inhibitor (HHIs) used as first-line systemic treatment for patients with advanced basal cell carcinoma (aBCC). Alopecia is reported as a frequent adverse event (AE), occurring in 49% of patients. Forty-five patients with aBCC were treated with sonidegib between December 2022 and December 2023; among them, 11/45 patients
Ciobotariu I +7 more
europepmc +8 more sources
Line-Field Confocal Optical Coherence Tomography Evaluation of Eyelid Skin Lesions [PDF]
Background: Periocular malignancies may be clinically different from the examples arising at other sites, with possible delayed diagnosis and greater challenges for treatment and repair.
Alessandro Di Stefani +16 more
doaj +3 more sources
Determination of scattering coefficient and scattering anisotropy factor of tissue-mimicking phantoms using line-field confocal optical coherence tomography (LC-OCT) [PDF]
Line-field Confocal Optical Coherence Tomography (LC-OCT) is an imaging modality based on a combination of time-domain optical coherence tomography and reflectance confocal microscopy.
Waszczuk Léna +3 more
doaj +3 more sources
Correlation of Vascular Patterns in Skin Lesions With LC-OCT and Dermoscopy With a Tridimensional Perspective: A Pilot Study [PDF]
Introduction: Vascular patterns play a crucial role in the diagnosis and differentiation of skin lesions by providing insight into underlying pathology and aid in distinguishing between benign and malignant lesions.
Clément Lenoir +14 more
doaj +2 more sources
Innovation in Actinic Keratosis Assessment: Artificial Intelligence-Based Approach to LC-OCT PRO Score Evaluation. [PDF]
Actinic keratosis (AK) is a common skin cancer in situ that can progress to invasive SCC. Line-field confocal optical coherence tomography (LC-OCT) has emerged as a non-invasive imaging technique that can aid in diagnosis. Recently, machine-learning algorithms have been developed that can automatically assess the PRO score of AKs based on the dermo ...
Daxenberger F +9 more
europepmc +3 more sources
The Role of (Line‐Field Confocal) Optical Coherence Tomography and Reflectance Confocal Microscopy in the Diagnosis of a Malignant Eccrine Differentiated Sweat Gland Tumour With Features of a Porocarcinoma and an Eccrine Spiradenocarcinoma: A Case Report [PDF]
Malignant eccrine differentiated sweat gland tumours, including porocarcinoma and eccrine spiradenocarcinoma, are rare and aggressive neoplasms that pose diagnostic and therapeutic challenges.
Sandra Schuh +10 more
doaj +2 more sources
Understanding the Dermoscopic Patterns of Basal Cell Carcinoma Using Line-Field Confocal Tomography [PDF]
Basal cell carcinoma (BCC) is the most frequent malignancy in the general population. To date, dermoscopy is considered a key tool for the diagnosis of BCC; nevertheless, line-field confocal optical coherence tomography (LC-OCT), a new non-invasive ...
Lorenzo Barbarossa +13 more
doaj +3 more sources
Non-invasive scoring of cellular atypia in keratinocyte cancers in 3D LC-OCT images using Deep Learning. [PDF]
Diagnosis based on histopathology for skin cancer detection is today's gold standard and relies on the presence or absence of biomarkers and cellular atypia. However it suffers drawbacks: it requires a strong expertise and is time-consuming. Moreover the
Fischman S +13 more
europepmc +2 more sources

