Results 121 to 130 of about 24,164 (284)
ANK1 and EPB41 Variants and The Risk of Steroid‐Induced Osteonecrosis
Arthritis &Rheumatology, Accepted Article.Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source
Lamina cribrosa curvature depth and index as novel parameters in Graves’ ophthalmopathy
Scientific ReportsThis study aims to evaluate lamina cribrosa (LC) parameters, macular ganglion cell layer thickness (GCLT) and peripapillary retina nerve fiber layer thickness (RNFLT) in Graves’ Ophthalmopathy (GO) patients using spectral domain optical coherence ...
Abdullah Ergen, Büşra Yılmaz Tuğan
doaj +1 more source
Epidemiology and risk factors of actinic keratosis. What is new for the management for sun-damaged skin [PDF]
Actinic keratosis (AK) is considered a chronic skin disease mostly caused by long-term exposure to UV radiation and other risk factors such as immunosuppression, leading to an individual susceptibility for skin cancer manifestation.
Schuh, Sandra +2 more
core +2 more sources
Arthritis &Rheumatology, Accepted Article.Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila +12 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +296 more
wiley +1 more source
ARTIFICIAL INTELLIGENCE-BASED INTEGRATED APPROACH FOR SKIN CANCER RECOGNITION [PDF]
Introduzione: l'incidenza del melanoma è in continuo aumento ed è responsabile della maggior parte dei decessi per tumore della pelle. La diagnosi precoce e la rimozione completa del tumore prima che inizi la fase di invasione profonda costituiscono le
SOGLIA, SIMONE
core
Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients
British Journal of Clinical Pharmacology, EarlyView.Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel +12 more
wiley +1 more source
Applied SciencesTo date, therapeutic responses in plaque psoriasis are evaluated with clinical scores. No objective examination has been established. A recently developed non-invasive imaging tool, line-field confocal optical coherence tomography (LC-OCT), enables the ...
Hanna B. Wirsching +8 more
doaj +1 more source
Enhancing the Management of High-Risk Basal Cell Carcinoma [PDF]
Basal cell carcinoma (BCC) is the most common skin cancer, with over 71,000 new cases in Sweden in 2023. High-risk facial BCCs are most appropriately treated with Mohs micrographic surgery (MMS), which is considered the gold standard.
Ceder, Hannah
core +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This study examines how plastics manufacturing firms can be classified according to their level of implementation of circular economy (CE) and industrial symbiosis (IS) practices and how such adoption influences sustainability performance. Using data from plastics manufacturing firms, we integrate cluster analysis with partial least squares ...
Laura Cristina Ramírez‐Rodríguez +3 more
wiley +1 more source