Results 251 to 260 of about 251,423 (287)

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source

Enhanced pitch centering in individuals with laryngeal dystonia. [PDF]

Front Hum Neurosci
Rangwala R, Subrahmanya A, Brent K, Gupta S, Ranasinghe K, Dale CL, Gaines JL, Pongos AL, Rosen CA, Schneider SL, Barkmeier-Kraemer J, Simonyan K, Houde JF, Nagarajan SS.   +13 more
europepmc   +1 more source

LD end-pumped c-cut Nd:YVO4 laser at 589 nm generated by sef-Raman conversion and frequency doubling

, 2011
Haiyong Zhu, Ge Zhang, Yaoju Zhang, Huang Cheng-Hui, Duan Yan-Min, Yong Wei, Pengfei Wei, Yongli Yu   +7 more
openalex   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Impact of maternal visceral leishmaniasis on sex-specific immune responses and pathogenesis in offspring following homologous infections. [PDF]

Front Immunol
Mizobuchi H, Sanjoba C, Goto Y.
europepmc   +1 more source

GO and KEGG pathways of differentially expressed mRNAs in beef liver at different age stages. (A) GO and KEGG pathways used to compare differentially expressed mRNAs between the LD and LM groups in yak liver. (B) GO and KEGG pathways used to compare differentially expressed mRNAs between the LD and LY groups in yak liver. (C) GO and KEGG pathways used to compare differentially expressed mRNAs between the LM and LY groups in yak liver.

Hongsen Fu (22394776), Wei Xia (349131), Fang Fu (507742), Jun Yi (839345), Wei Wang (17594), Yong Wei (44544), Li Wang (15202)   +6 more
openalex   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma. [PDF]

Adv Sci (Weinh)
Qi X, Guo Y, Yang Y, Wang H, Yang X, Song R, Qin Q, Zhang Y, Hu M, Zhou H, Feng D, He J.   +11 more
europepmc   +1 more source

Calculated output powers of 1297 nm and 1306 nm versus pump beam waist location at LD operating temperature = 32 °C.

Chu Chu (6210905), Xinghua Yang (519671), Yuzhao Li (10700146)   +2 more
openalex   +1 more source