Results 141 to 150 of about 118,657 (309)

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

open access: yesBiotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney   +6 more
wiley   +1 more source

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

open access: yesBiotechnology and Bioengineering, EarlyView.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse   +3 more
wiley   +1 more source

FROM WORDS TO SHOCKS: Textual Analysis and Inquiry into the Explanation of DSGE-Inferred Shocks Using Monetary Policy Text in Pakistan

open access: yesPakistan Journal of Applied Economics
This paper uses Natural Language Processing (NLP) techniques to discern how central bank communication in an emerging economy gets shaped during normal and crisis periods and across different governors’ tenures.
AteebAkhter Shah SYED   +2 more
doaj  

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

open access: yesBMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao   +9 more
wiley   +1 more source

Spatial metrics in fire ecology: seeking consistency amidst complexity

open access: yesBiological Reviews, EarlyView.
ABSTRACT Technological advances, including remote sensing, have led to a proliferation of metrics used in ecological studies to examine spatial patterns of fire regimes and their ecological effects. Researchers can use many different metrics to analyse spatial variation in both fire events and resulting fire regimes, including fire size, shape ...
Alexander R. Carey   +5 more
wiley   +1 more source

Harnessing Generative AI for Sustainable Supply Chains: Lean, Circular and Green Perspectives

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Generative artificial intelligence is playing a significant role in the transformation of digital ecosystems by reinventing the processes of content generation, process automation, product innovation and customer experience. At the same time that these technologies are becoming more integrated into routine operations, the focus has shifted to ...
Ashutosh Singh   +3 more
wiley   +1 more source

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