Results 231 to 240 of about 302,479 (284)

Reassessing LDL-C thresholds: Toward tailored lipid management

Journal of the Formosan Medical Association
Yu-Chung Hsiao, Tzu-Yang Chen, Fang-Ju Lin, Chau-Chung Wu   +3 more
openaire   +2 more sources

Cardiovascular risk profile according to World Health Organization medical eligibility criteria for contraceptive use of women using hormonal contraception in Rio de Janeiro state, Brazil

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Hormonal contraception, especially combined oral contraceptives, is associated with an increase in cardiovascular risk. Thus, we aimed to analyze the use of hormonal contraceptive methods in the state of Rio de Janeiro (Brazil), with a focus on determining whether contraceptive use follows the cardiovascular profile of women ...
Isabela Pereira Fonseca Brusth, Juliana Montani Raimundo, Helene Nara Henriques Blanc   +2 more
wiley   +1 more source

"Inclisiran: Early LDL-C target achievement in a real-life population". [PDF]

Atheroscler Plus
Briani F, Bagli M, Venturi G, Bacchion F, Mugnolo A.   +4 more
europepmc   +1 more source

Oat β‐Glucan and Galactooligosaccharides Influence Gallstone Formation by Modulating the Gut Microbiota, Particularly Desulfovibrionales

iMetaMed, EarlyView.
Oat β‐glucan and galactooligosaccharides influence the formation of gallstones by modulating the gut microbiota, particularly the abundance of Desulfovibrionales. The primary mechanism involves metabolic byproducts associated with Desulfovibrionales inhibiting hepatic bile acid synthesis via both the hepatic FXR–SHP and intestinal FXR–FGF15 signaling ...
Liang Tian, Yanyan Lin, Ping Yue, Long Gao, Leiqing Wang, Chongfei Huang, Jinyu Zhao, Ningzu Jiang, Jiahui xi, Haidong Ma, Zhen Liu, Ruyang Zhong, Wenkang Fu, Ningning Mi, Mingzhen Bai, Bodong Zhang, Lunzhi Dai, Jiang Li, Hu Chen, Jinqiu Yuan, Wenbo Meng   +20 more
wiley   +1 more source

Moving Beyond LDL-C and Non-HDL-C: Apolipoprotein B as the Stronger Lipid-Related Predictor of Coronary Artery Disease in Statin-Treated Patients. [PDF]

Diagnostics (Basel)
Jigoranu RA, Mitu O, Costache AD, Oancea A, Miftode RS, Buburuz AM, Bazyani A, Simion P, Gavril RS, Cianga P, Harnau MS, Onofrei V, Petris AO, Costache Enache II, Mitu F.   +14 more
europepmc   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Imbalances in circulating monocyte and high-density lipoprotein cholesterol exacerbates the residual risk of incident myocardial infarction beyond LDL-C: a real-life, prospective cohort study. [PDF]

J Transl Med
Wu D, Lan Y, Ding X, Balmer L, Li X, Wang W, Wu S, Chen Y.   +7 more
europepmc   +1 more source

Therapeutic Gene Editing: DNA Repair Pathways, Emerging Editors, and Clinical Progress

iNew Medicine, EarlyView.
ABSTRACT The field of gene editing has evolved rapidly over the past decade, progressing from programmable zinc‐finger nucleases (ZFNs) and transcription activator‐like effector nucleases (TALENs) to the widespread adoption of CRISPR‐Cas systems. First‐generation editors catalyzed genome engineering by introducing targeted double‐strand breaks (DSBs ...
Li‐Kuang Tsai, Youcai Xiong, Dongqi Liu, Dongshan Yang, Jifeng Zhang, Jie Xu, Renzhi Han, Y. Eugene Chen   +7 more
wiley   +1 more source

Editorial: Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins. [PDF]

Front Cardiovasc Med
De Caterina R, Budoff M, Boden WE.
europepmc   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source