Results 21 to 30 of about 42,411 (207)

Variación en el consumo de leña y factores que lo determinan en una comunidad campesina al suroeste del estado de Morelos, México

Botan‪ical Sciences, 2022
Antecedentes: La leña es el principal recurso energético de las familias rurales en diversas comunidades de México. En Morelos el 6.2 % de las viviendas particulares utilizan este recurso para cocinar y la Selva Baja Caducifolia es el principal tipo de ...
Mónica Bello-Román, Alejandro García-Flores, Hortensia Colín-Bahena, Erika Román-Montes de Oca, Leonardo Beltrán-Rodríguez   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Usos de los bosques como leña y sus efectos en el ecosistema : el caso de la sierra central de Piura, Perú

Espacio y Desarrollo, 1993
El incremento poblacional viene acelerando la destrucción de los bosques, al punto que ya existen zonas donde las poblaciones consumen buena parte de su tiempo sólo en colectar leña para sus cocinas. En la siguiente investigación se hace un análisis de
Hildegardo Córdova Aguilar
doaj  

Exploring Mothers’ Experience of a Linguistic Feedback Technology for Children at Risk of Poor Language Development: Qualitative Pilot Study

JMIR Pediatrics and Parenting, 2021
BackgroundThe early language environment is important for language development and a child’s life-course trajectory. Risk factors associated with poor language development outcomes in children include maternal anxiety and ...
Lydia So, Erin Miller, John Eastwood
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Caracterización del sistema agrosilvopastoril en la Depresión Central de Chiapas

AIA Avances en Investigación Agropecuaria, 2012
A través de talleres participativos, se analizó la importancia de algunos árboles para el manejo de los sistemas productivos en una comunidad zoque, del municipio de Ocozocuautla de Espinosa, Chiapas (México).
N. Ramírez-Marcial, M. L. Rueda-Pérez, B. G. Ferguson, G. Jiménez-Ferrer   +3 more
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

El aprovisionamiento de leña en las ciudades de la baja edad media hispánica

Estudios de Historia de España, 2016
In recent years studies on the supply in Medieval Spain, has increased considerably. In our country, Dra. Carlé has been a pioneer in these topics by opening the doors to novice researchers. This time, the aim of this paper is to show how it is perceived
Jorge R. Estrella, Alberto Asla
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source