Results 221 to 230 of about 2,085,593 (298)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Zero superior vena cava injury lead extraction with rotational system: A contemporary experience. [PDF]

open access: yesJTCVS Open
Williams IE   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effective and safe mechanical transvenous lead extraction in a low-volume center. [PDF]

open access: yesHeart Rhythm O2
Li L   +5 more
europepmc   +1 more source

Hybrid procedure: mini-invasive tricuspid valve plasty with transvenous lead extraction. [PDF]

open access: yesKardiochir Torakochirurgia Pol
Gozdek J   +6 more
europepmc   +1 more source

Impact of hospital lead extraction volume on management of cardiac implantable electronic device-associated infective endocarditis. [PDF]

open access: yesEuropace
Mandler AG   +12 more
europepmc   +1 more source

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