Results 101 to 110 of about 7,252,354 (295)

Does "model-free" forecasting really outperform the "true" model? A reply to Perretti et al

, 2013
Estimating population models from uncertain observations is an important problem in ecology. Perretti et al. observed that standard Bayesian state-space solutions to this problem may provide biased parameter estimates when the underlying dynamics are ...
Dormann, Carsten F., Hartig, Florian
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Lead-free piezoceramics – Where to move on?

Journal of Materiomics, 2016
Lead-free piezoceramics aiming at replacing the market-dominant lead-based ones have been extensively searched for more than a decade worldwide. Some noteworthy outcomes such as the advent of commercial products for certain applications have been ...
Chang-Hyo Hong, Hwang-Pill Kim, Byung-Yul Choi, Hyoung-Su Han, Jae Sung Son, Chang Won Ahn, Wook Jo   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

How efficient are metal‐polymer and dual‐metals‐polymer non‐lead radiation shields?

Journal of Medical Radiation Sciences
Introduction Lead shields are often used to attenuate ionising radiations. However, to make lighter, recyclable and more efficient shields compared to lead, combinations of new metallic compounds together with polymer, for example, flexible polyvinyl ...
Zaker Salehi, Mansour Tayebi Khorami
doaj   +1 more source

X-ray lead equivalent measurement of lead-free/lead-composite nuclear radiation protection materials

He jishu
BackgroundLead-free/lead-composite nuclear radiation protection materials are becoming increasingly prevalent in military applications to safeguard the health and safety of military personnel.
ZHAO Rui, WU Jinjie, LIU Bo, TANG Xianqiang, GUO Bin, LYU Yazhu, HAN Lu   +6 more
doaj   +1 more source

Impedance spectroscopy studies on lead free (Ba0.85Ca0.15)(Ti0.9Zr0.1)O3 ceramics [PDF]

Processing and Application of Ceramics, 2012
The AC complex impedance spectroscopy technique has been used to obtain the electrical parameters of polycrystalline sample of (Ba0.85Ca0.15)(Ti0.9Zr0.1)O3 in a wide frequency range at different temperatures.
Ahcène Chaouchi, Sadia Kennour
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source