Results 71 to 80 of about 13,515 (191)
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
The Journal of Physiology, EarlyView.Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
P428Usefulness of SPECT-CT with radioisotope-labeled leukocytes for diagnosis of lead-dependent infective endocarditis [PDF]
EP Europace, 2017 B. Malecka +6 more
openaire +1 more source
Advanced Oncology, Volume 1, Issue 1, December 2026.ABSTRACT The avian eggshell is a sophisticated, multi‐functional biocomposite and, more importantly, an autonomous life‐support system evolved to safeguard embryonic development across dynamic and hostile environments. Discussing eggshell‐inspired biomaterials beyond simple structural imitation, this review translates these evolutionary survival ...
Zhiqiang Liu +11 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.Routine radioactive iodine (RAI) after thyroidectomy in low‐risk differentiated thyroid cancer shows no clear benefit in reducing recurrence or improving survival. These findings support a selective, risk‐based approach, avoiding unnecessary treatment and potential adverse effects.
Maheen Asif +5 more
wiley +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur
Experimental Physiology, EarlyView.
Anders Møller Greve +4 more
wiley +1 more source
Prostate Cancer Development, Progression, and Therapy
MedComm – Oncology, Volume 5, Issue 3, September 2026.This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
Dose modeling of superficial brachytherapy applicator geometries using multiple radioisotopes
Medical Physics, Volume 53, Issue 9, September 2026.Abstract Background Superficial brachytherapy enables localized dose delivery for superficial cutaneous lesions, but conventional applicators may be limited in treating extended, irregular, or curved surfaces. Geometric constraints, gaps or overlaps between adjacent applicators, and placement‐related uncertainties can reduce dose uniformity ...
Jin Jegal +5 more
wiley +1 more source
Multi‐fidelity Monte Carlo fusion for BNCT dose calculation using a dual‐branch network
Medical Physics, Volume 53, Issue 9, September 2026.Abstract Background Boron neutron capture therapy (BNCT) is a binary radiotherapy that selectively kills tumor cells. Its clinical implementation relies on Monte Carlo (MC)‐based treatment planning systems, which are time‐consuming and limit clinical workflow efficiency.
Leiming Li +7 more
wiley +1 more source