Results 111 to 120 of about 606,542 (313)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Τοπική ανάπτυξη και πρωτοβουλία Leader: γεωγραφική ανάλυση επενδύσεων στην Ελλάδα

open access: yes, 2015
Η παρούσα διπλωματική εργασία έχει ως στόχο την ανάλυση των αποτελεσμάτων της εφαρμογής του προγράμματος Leader στον αγροτικό χώρο των διαφόρων περιφερειών της Ελλάδας.
Αλατζάς, Ευάγγελος - Παναγιώτης
core  

University Leader - May 9, 1977 [PDF]

open access: yes, 1977
This four page student newspaper titled University Leader was published for the student body at Fort Hays State University in Hays ...
University Leader Staff
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

University Leader - May 5, 1977 [PDF]

open access: yes, 1977
This four page student newspaper titled University Leader was published for the student body at Fort Hays State University in Hays ...
University Leader Staff
core  

THE TRANSFORMATION OF RURAL COMMUNITIES THROUGH URBAN TO RURAL RELOCATION. MARKETING STRATEGIES IN SUSTAINABLE DEVELOPMENT [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Urban-rural relocation has become a growing trend in Europe and Romania, driven by the desire for healthier, more sustainable lifestyles and enabled by remote work technologies.
MIHĂLCEANU (STAN) ECATERINA
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

LEADER pályázatok szerepe Nagycsécs fejlődésében

open access: yes, 2014
Szakdolgozatomban a LEADER csoportok fontosságára próbálok rávilágítani. Szakdolgozatomban választ kapunk a legfontosabb felmerülő kérdésre, arra, hogy milyen jelentős szerepük van a LEADER pályázatoknak a vidéki települések fejlődésében, hiszen a szűkös
Leskó, Beáta
core  

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