Results 101 to 110 of about 1,718,225 (251)

Evaluation of Rural Surrey LEADER Programme 2008-2022

open access: yes, 2022
The report presents the findings of an evaluation of the Rural Surrey LEADER programme conducted for Surrey County Council and Rural Surrey Local Action Group.
Jessica Sellick (17186671)   +3 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

COPD Outreach Programme Model of Care [PDF]

open access: yes, 2010
The Health Service Executive Transformation Programme (2006) identified chronic disease management as a priority (HSE, 2006), and concluded that existing therapeutic models are not meeting the current and future needs of this cohort of patients.
National COPD Programme Working Group
core  

Economic Situations, Expansion-crisis, and the Effect Of Rural Development policies: The Case of Castilla-La Mancha, Spain

open access: yesJournal of Rural and Community Development
In 1991, over thirty years ago, the European Commission’s [EC] LEADER initiative was set up to revitalize the rural environment using its endogenous potential. Although it is now fully consolidated as a public action and despite of the great interest it
Francisco Martínez-Arroyo   +3 more
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

National literacy programme: Jamaica - (Mission). Project findings and recommendations

open access: yes, 1976
This is a mission report on a literacy programme in Jamaica, with particular emphasis on various utilizations of the mass media. It describes the establishment of a printing workshop and training courses for literacy workers, including inservice teacher ...
United Nations Development Programme
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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