Results 41 to 50 of about 1,718,225 (251)
THE ACTIVITY OF LOCAL ENTERPRISES OF THE WEST-PANNON REGION IN THE LEADER+ PROGRAM A NYUGAT-DUNÁNTÚLI RÉGIÓ VÁLLALKOZÁSAINAK AKTIVITÁSA A LEADER+ PROGRAMBAN [PDF]
The Leader programme was launched to realign the mainstreaming of the European Union’s development policy. In the program period 2004 – 2006 in Hungary, the community initiative was a measure of the National Development Plan’s Operative Programme for ...
Dóra SZILI-FODOR
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Integrated projects of rural microregions: Experiences in the Central Bohemia region
The article brings the empiric reflection and results-based analysis of the "Programme of Rural Revival" realization in the territory of the Central Bohemia Region (NUTS II/III) in the time of regional self-governing organization in the Czech Republic ...
V. Mlejnecká, L. Kříž
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Évaluation régionale LEADER en Auvergne : un bilan mitigé et contrasté en termes de valeur ajoutée
Introduit par la communauté européenne au début des années 1990 pour remédier aux difficultés structurelles de développement des territoires ruraux, le programme d'initiative communautaire LEADER s'est affirmé.
J. MATHÉ +3 more
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Portraying the role: Exploring support needs of Programme Leaders in HE through portraiture
Programme Leaders (PLs) in Higher Education (HE) hold a complex role that has responsibilities that link to external performance metrics. This role, existing outside of the traditional teaching/research view means it often lacks visibility and esteem ...
Jemma Oeppen Hill
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The programmes to be implemented through the structural funds in Finland are Objective 1, 2 and 3 programmes as well as Community Initiatives LEADER+, INTERREG III, EQUAL and URBAN.
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