Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Comparative deep learning approaches for bean leaf disease recognition. [PDF]
Anirudh K, Srujan D, Sai A, O V GS.
europepmc +1 more source
This study proposes a patch‐type tremor monitoring system based on high‐repeatable fibrous crack‐based strain sensor, capable of simultaneously measuring tremor in multiple locations such as thumb, index, and wrist. Through clinical trials involving Parkinson's disease and essential tremor patients, the proposed system demonstrates its potential as a ...
Chiwon Song +12 more
wiley +1 more source
QTL mapping, validation, and candidate gene predicting for maize plant architecture traits via bulked segregant analysis plus linkage analysis with F₂ population. [PDF]
Wang S, Wang Y, Li X, Ge B, Su C.
europepmc +1 more source
Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang +11 more
wiley +1 more source
LSL-YOLO11n: a YOLO11n-based model for maize leaf disease detection in complex field environments. [PDF]
Yang C +6 more
europepmc +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
Dissection of the Genetic Basis of Maize Plant Architecture and Candidate Gene Mining Based on the MAGIC Population. [PDF]
Xu X +7 more
europepmc +1 more source
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang +20 more
wiley +1 more source
Drought adaptation in spring wheat seedlings relies on coordinated deep root architecture and cortical tissue allocation. [PDF]
Li X +9 more
europepmc +1 more source

