Results 91 to 100 of about 166,280 (191)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
League-ally Speaking was a newsletter published by the Toledo League for the Hard of Hearing in Toledo, Ohio. Incorporated in 1920, the organization was also an agency of the Toledo Community Chest. In 1947 the organization changed its name to the Toledo
Toledo League for the Hard of Hearing
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Gender Justice League Sticker with Logo
, 2015 A sticker with the Gender Justice League logo on it handed out at advocacy events and other trans rights ...
Gender Justice League
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Guan'gai paishui xuebao【Objective】Populus euphratica is widely grown in Xinjiang, Northwestern China. The growth and development of its understory herbaceous plants are influenced by various factors.
LI Jia +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Vereinsbote : the Walther League messenger.
, 1918 Description based on: Vol. 23, no.
Walther League.
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Scientific ReportsAdolescent insomnia constitutes a prominent public health priority, frequently co-occurring with psychological distress and digital media dependence. This study evaluated the distribution of shared variance among physical activity, anxiety, short video ...
Yuhao Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Report of the Australasian White Cross League.
, 1900 Description based on: 1915; Also available online at: http://nla.gov.au/nla.aus-vn2224173; FERG copy from Ferguson First World War, 1914-1919 pamphlet ...
Australasian White Cross League.
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Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source