Results 41 to 50 of about 257,938 (301)
Confidence-leak: Data and code
, 2015 <p>Data and code for paper: Rahnev, D., Koizumi, A., McCurdy, L.Y., D’Esposito, M., & Lau, H. (in press). Confidence leak in perceptual decision-making.
Dobromir Rahnev
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Clinical Case Reports, 2018 Key Clinical Message Aberrant subvesical bile ducts are rare anatomical structures. Damage to these ducts leads to bile leakage and can result in life‐threatening complications.
Sanghyun Song, Sungho Jo
doaj +1 more source
Laboratory Investigation of the Leakage Characteristics of Unburied HDPE Pipes [PDF]
, 2015 In this research work, the leakage characteristics of the viscoelastic material HDPE is investigated and compared to other materials like uPVC which is elastic and galvanised steel which is rigid in nature. Under no axial loading, the deformation in HDPE
King, R.T.F. Ah +4 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Detection of Gate Valve Leaks through the Analysis Fractal Characteristics of Acoustic Signal
Fractal and FractionalThis paper considers the possibility of using monofractal and multifractal analysis of acoustic signals to detect water leaks through gate valves. Detrended fluctuation analysis (DFA) and multifractal detrended fluctuation analysis (MF-DFA) were used ...
Ayrat Zagretdinov +5 more
doaj +1 more source
Frontiers in Physiology, 2022 The intricate regulation of the compartmental Ca2+ concentrations in cardiomyocytes is critical for electrophysiology, excitation-contraction coupling, and other signaling pathways.
Molly E. Streiff +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Use of Machine Learning for Leak Detection and Localization in Water Distribution Systems
Smart Cities, 2021 This paper presents an investigation of the capacity of machine learning methods (ML) to localize leakage in water distribution systems (WDS). This issue is critical because water leakage causes economic losses, damages to the surrounding infrastructures,
Neda Mashhadi +4 more
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source