Results 41 to 50 of about 518,024 (300)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

EXPERIMENTAL ASSESSMENT OF LEAKAGE CURRENT MAGNITUDE IN AUTOMATIC FOAM FIRE SUPPRESSION SYSTEMS [PDF]

Актуальные вопросы пожарной безопасности
The article presents the results of an experimental study of leakage currents that occur during the operation of automatic foam extinguishing systems (AUPT).
Alexandr M. Solonenko, Mikhail V. Shishkov, Andrey Yu. Mazurenko, Pavel G. Aksyutin   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Computationally Efficient Hybrid Leakage Model for Modeling Leakage in Positive Displacement Compressors [PDF]

, 2012
An empirical frictional correction factor to the isentropic nozzle model has been developed for application to leakage modeling in scroll, rotary and other similar compressors. This correction factor is derived by calculating the leakage mass flow with a
Groll, Eckhard A., Braun, James E., Horton, W. Travis, Bell, Ian H.   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Asymmetric gate induced drain leakage and body leakage in vertical MOSFETs with reduced parasitic capacitance

, 2006
Vertical MOSFETs, unlike conventional planar MOSFETs, do not have identical structures at the source and drain, but have very different gate overlaps and geometric configurations.
Ashburn, P., Gili, E., Kunz, D., Hakim, M.M.A., Uchino, T., Hall, S., de Groot, C.H.   +6 more
core   +1 more source

A Hybrid Gate Dielectrics of Ion Gel with Ultra-Thin Passivation Layer for High-Performance Transistors Based on Two-Dimensional Semiconductor Channels

Scientific Reports, 2017
We propose a hybrid gate structure for ion gel dielectrics using an ultra-thin Al2O3 passivation layer for realizing high-performance devices based on electric-double-layer capacitors. Electric-double-layer transistors can be applied to practical devices
Hyunjin Jo, Jeong-Hun Choi, Cheol-Min Hyun, Seung-Young Seo, Da Young Kim, Chang-Min Kim, Myoung-Jae Lee, Jung-Dae Kwon, Hyoung-Seok Moon, Se-Hun Kwon, Ji-Hoon Ahn   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Leakage current reduction for a double-leg boost converter by switching transition synchronisation

The Journal of Engineering, 2019
With wide-bandgap transistors, the leakage current through the parasitic transistor to heat sink capacitance is increased with the operation at higher switching transition voltage slopes.
Matthias Zehelein, Johannes Ruthardt, Maximillian Nitzsche, Tobias Tymosch, Jörg Roth-Stielow   +4 more
doaj   +1 more source

Optical Sensor for Monitoring Leakage Current and Weather Conditions in a 500-kV Transmission Line

Sensors, 2022
The leakage current (LC) caused by the surface contamination of insulators, together with environmental variables, is one of the most basic online monitoring parameters for insulator status.
Marcelo M. Werneck, Paulo Henrique S. Pinto, Renato T. Bellini, Regina Célia S. B. Allil   +3 more
doaj   +1 more source