Results 41 to 50 of about 89,125 (297)

Present situation and development trend of control and protection technology for mine-used combined switch

open access: yesGong-kuang zidonghua, 2019
Present situation of control and protection technology for mine-used combined switch was introduced from aspects of short circuit protection, overload protection, leakage lockout and leakage protection, transient overvoltage protection and temperature ...
YANG Fan, CHEN Jiang
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Understanding privacy leakage concerns in Facebook: A longitudinal case study [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityThis thesis focuses on examining users’ perceptions of privacy leakage in Facebook – the world’s largest and most popular social network site (SNS).
Jamal, Arshad
core  

Design of Selective Leakage Protection Circuit Based on Method of Amplitude Discrimination and Phase Discriminatio

open access: yesGong-kuang zidonghua, 2010
The paper proposed a design scheme of selective leakage protection circuit based on method of amplitude discrimination and phase discrimination for electrical control equipments of fully mechanized devices of coal mine underground.The selective leakage ...
FAN Yi-long~, LI Hang~, YOU Guo-dong~
doaj  

Protecting Digital Dignitas: Highlighting Legal Protection and Responsibility in Personal Data Security Crime in Indonesia's Online Marketplace World

open access: yesMahadi, 2023
Today the development of technology is increasingly massive and gave birth to a form of intelligence called Artificial Intelligence/AI. Economic potential and threats of personal data leakage awaiting immediate investigation.
Dinda Yunisa   +3 more
doaj   +1 more source

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